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Kivexa
Eintrag öffnenKivexa · 4.1 Therapeutic indications · 1
Eintrag öffnenKivexa · 4.3 Contraindications · 1
Eintrag öffnenKivexa · 4.3 · Hypersensitivity to the active substances or to any of the excipients listed in section 6.1. See sections 4.4
Eintrag öffnenKivexa · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenKivexa · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenKivexa · 4.5 · 7 patients should be monitored (organic cation transporter clinically. High doses of inhibition) trimethoprim/
Eintrag öffnenKivexa · 4.5 · 8 Drugs by Therapeutic Area Interaction Recommendation concerning Geometric mean change (%) co-administration
Eintrag öffnenKivexa · 4.5 · 9 Drugs by Therapeutic Area Interaction Recommendation concerning Geometric mean change (%) co-administration
Eintrag öffnenKivexa · 4.5 · Abacavir and lamivudine are not significantly metabolised by cytochrome P450 enzymes (such as CYP 3A4, CYP 2C9
Eintrag öffnenKivexa · 4.5 · Abacavir is metabolised by UDP-glucuronyltransferase (UGT) enzymes and alcohol dehydrogenase; co-administratio
Eintrag öffnenKivexa · 4.5 · Clinically significant interaction unlikely. Cimetidine eliminated only in part by renal organic cation transp
Eintrag öffnenKivexa · 4.5 · Clinically significant interaction unlikely. Ranitidine eliminated only in part by renal organic cation transp
Eintrag öffnenKivexa · 4.5 · Drugs by Therapeutic Area Interaction Recommendation concerning Geometric mean change (%) co-administration (P
Eintrag öffnenKivexa · 4.5 · Interaction studies have only been performed in adults.
Eintrag öffnenKivexa · 4.5 · Kivexa contains abacavir and lamivudine, therefore any interactions identified for these individually are rele
Eintrag öffnenKivexa · 4.5 · Kivexa should not be taken with any other medicinal products containing lamivudine (see section 4.4).
Eintrag öffnenKivexa · 4.5 · Paediatric population
Eintrag öffnenKivexa · 4.5 · RETINOIDS Retinoid compounds Interaction not studied. Insufficient data to (e.g. isotretinoin)/Abacavir recomm
Eintrag öffnenKivexa · 4.5 · The list below should not be considered exhaustive but is representative of the classes studied.
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