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Latuda
Eintrag öffnenLatuda · 4.1 Therapeutic indications · 1
Eintrag öffnenLatuda · 4.3 Contraindications · 1
Eintrag öffnenLatuda · 4.3 · - Hypersensitivity to the active substance or to any of the excipients listed in section 6.1. - Concomitant ad
Eintrag öffnenLatuda · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenLatuda · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenLatuda · 4.5 · 5 Latuda should be used cautiously when co-administered with other serotonergic agents, such as buprenorphine/
Eintrag öffnenLatuda · 4.5 · 6 Potential for lurasidone to affect other medicinal products Coadministration of lurasidone with midazolam, a
Eintrag öffnenLatuda · 4.5 · A clinical drug interaction study investigating the effect of coadministration of lurasidone on patients takin
Eintrag öffnenLatuda · 4.5 · CYP3A4 inducers Lurasidone is contraindicated with strong CYP3A4 inducers (e.g. carbamazepine, phenobarbital,
Eintrag öffnenLatuda · 4.5 · CYP3A4 inhibitors Lurasidone is contraindicated with strong CYP3A4 inhibitors (e.g. boceprevir, clarithromycin
Eintrag öffnenLatuda · 4.5 · Caution is advised when prescribing lurasidone with medicinal products known to prolong the QT interval, e.g.
Eintrag öffnenLatuda · 4.5 · Co-administration of lurasidone and posaconazole (strong CYP3A4 inhibitor) resulted in an approximate 4-5 fold
Eintrag öffnenLatuda · 4.5 · Coadministration of lurasidone with digoxin (a P-gp substrate) did not increase the exposure to digoxin and on
Eintrag öffnenLatuda · 4.5 · Coadministration of lurasidone with diltiazem (slow-release formulation), a moderate CYP3A4 inhibitor, resulte
Eintrag öffnenLatuda · 4.5 · Coadministration of lurasidone with lithium indicated that lithium had clinically negligible effects on the ph
Eintrag öffnenLatuda · 4.5 · Coadministration of lurasidone with medicinal products that moderately inhibit CYP3A4 (e.g. diltiazem, erythro
Eintrag öffnenLatuda · 4.5 · Coadministration of lurasidone with mild (e.g. armodafinil, amprenavir, aprepitant, prednisone, rufinamide) or
Eintrag öffnenLatuda · 4.5 · Coadministration of lurasidone with the strong CYP3A4 inducer rifampicin resulted in a 6-fold decrease in expo
Eintrag öffnenLatuda · 4.5 · Coadministration of lurasidone with the strong CYP3A4 inhibitor ketoconazole resulted in a 9- and 6-fold incre
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