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Libtayo
Eintrag öffnenLibtayo · 4.1 Therapeutic indications · 1
Eintrag öffnenLibtayo · 4.3 Contraindications · 1
Eintrag öffnenLibtayo · 4.3 · Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Eintrag öffnenLibtayo · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenLibtayo · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenLibtayo · 4.5 · No pharmacokinetic (PK) drug-drug interaction studies have been conducted with cemiplimab. The use of systemic
Eintrag öffnenLibtayo · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenLibtayo · 4.8 Undesirable effects · 1
Eintrag öffnenLibtayo · 4.8 · 11 The safety of cemiplimab in combination with platinum‐based chemotherapy has been evaluated in a clinical s
Eintrag öffnenLibtayo · 4.8 · 12 Meningitisj Rare < 0.1 < 0.1 Encephalitis Rare < 0.1 < 0.1 Myasthenia Gravis Rare < 0.1 0 Paraneoplastic Ra
Eintrag öffnenLibtayo · 4.8 · 13 Aspartate aminotransferase Common 4.4 0.7 Very common 14.7 0.3 increased Blood alkaline phosphatase Common
Eintrag öffnenLibtayo · 4.8 · 14 dd. Oedema includes peripheral oedema, face oedema, peripheral swelling, face swelling, localised oedema, g
Eintrag öffnenLibtayo · 4.8 · 15 9 days to 32.7 months). Resolution of hyperthyroidism had occurred in 22 (56.4%) of the 39 patients at the
Eintrag öffnenLibtayo · 4.8 · 16 Musculoskeletal and connective tissue disorders: Arthralgia (1.2%), arthritisd, muscular weakness, myalgia,
Eintrag öffnenLibtayo · 4.8 · Adrenal insufficiency occurred in 6 (0.5%) of 1281 patients receiving cemiplimab, including 6 (0.5%) patients
Eintrag öffnenLibtayo · 4.8 · Adverse events led to permanent discontinuation of cemiplimab in 5.1% of patients.
Eintrag öffnenLibtayo · 4.8 · Adverse events led to permanent discontinuation of cemiplimab in 9.4% of patients.
Eintrag öffnenLibtayo · 4.8 · Adverse events led to permanent discontinuation of cemiplimab in 9.8% of patients.
Eintrag öffnenLibtayo · 4.8 · Adverse events were serious in 17.6% of patients.
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