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Loqtorzi
Eintrag öffnenLoqtorzi · 4.1 Therapeutic indications · 1
Eintrag öffnenLoqtorzi · 4.3 Contraindications · 1
Eintrag öffnenLoqtorzi · 4.3 · Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Eintrag öffnenLoqtorzi · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenLoqtorzi · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenLoqtorzi · 4.5 · No formal interaction studies have been performed. Since toripalimab is cleared from the circulation through c
Eintrag öffnenLoqtorzi · 4.5 · The use of systemic corticosteroids or immunosuppressants before starting toripalimab should be avoided becaus
Eintrag öffnenLoqtorzi · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenLoqtorzi · 4.8 Undesirable effects · 1
Eintrag öffnenLoqtorzi · 4.8 · 10 Very common neuropathy5 Common dizziness, headache, neurotoxicity, dysgeusia Uncommon somnolence, syncope,
Eintrag öffnenLoqtorzi · 4.8 · 11 Uncommon muscle spasms, intervertebral disc protrusion, myositis Rare limb mass Renal and urinary disorders
Eintrag öffnenLoqtorzi · 4.8 · 12 Description of selected adverse reactions Data for the following immune-related adverse reactions are based
Eintrag öffnenLoqtorzi · 4.8 · 13 In patients receiving toripalimab in JUPITER-02 and JUPITER-06, diabetes mellitus occurred in 0.2% (1/403)
Eintrag öffnenLoqtorzi · 4.8 · 14 discontinuation of toripalimab in 3 (0.2%) patients. Common symptoms of infusion-related reaction include f
Eintrag öffnenLoqtorzi · 4.8 · 9 an adverse reaction may have other causes than the medicinal product such as the disease, other medicines or
Eintrag öffnenLoqtorzi · 4.8 · Elderly Of the 403 patients treated with toripalimab in combination with platinum-based chemotherapy in clinic
Eintrag öffnenLoqtorzi · 4.8 · Hepatotoxicity and immune-related hepatitis Immune-related hepatitis occurred in 2.0% (8/403) of patients rece
Eintrag öffnenLoqtorzi · 4.8 · Hypothyroidism occurred in 17.1% (69/403) of patients receiving toripalimab in JUPITER-02 and JUPITER-06, with
Eintrag öffnenLoqtorzi · 4.8 · Immune-related adverse reactions (see section 4.4)
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