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Mysildecard
Eintrag öffnenMysildecard · 4.1 Therapeutic indications · 1
Eintrag öffnenMysildecard · 4.3 Contraindications · 1
Eintrag öffnenMysildecard · 4.3 · 3 Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Eintrag öffnenMysildecard · 4.3 · Co-administration with nitric oxide donors (such as amyl nitrite) or nitrates in any form due to the hypotensi
Eintrag öffnenMysildecard · 4.3 · Combination with the most potent of the CYP3A4 inhibitors (e.g. ketoconazole, itraconazole, ritonavir) (see se
Eintrag öffnenMysildecard · 4.3 · Patients who have loss of vision in one eye because of non-arteritic anterior ischaemic optic neuropathy (NAIO
Eintrag öffnenMysildecard · 4.3 · The co-administration of PDE5 inhibitors, including sildenafil, with guanylate cyclase stimulators, such as ri
Eintrag öffnenMysildecard · 4.3 · The safety of sildenafil has not been studied in the following sub-groups of patients and its use is therefore
Eintrag öffnenMysildecard · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenMysildecard · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenMysildecard · 4.5 · 6 CYP3A4 inducers seemed to have a substantial impact on the pharmacokinetics of sildenafil in pulmonary arter
Eintrag öffnenMysildecard · 4.5 · 7 Co-administration of oral contraceptives (ethinyloestradiol 30 μg and levonorgestrel 150 μg) did not affect
Eintrag öffnenMysildecard · 4.5 · 8 Sildenafil (100 mg single dose) did not affect the steady state pharmacokinetics of the HIV protease inhibit
Eintrag öffnenMysildecard · 4.5 · Addition of a single dose of sildenafil to sacubitril/valsartan at steady state in patients with hypertension
Eintrag öffnenMysildecard · 4.5 · Co-administration of bosentan (a moderate inducer of CYP3A4, CYP2C9 and possibly of CYP2C19) 125 mg twice dail
Eintrag öffnenMysildecard · 4.5 · Co-administration of oral sildenafil and intravenous epoprostenol has been evaluated (see sections 4.8 and 5.1
Eintrag öffnenMysildecard · 4.5 · Co-administration of the HIV protease inhibitor ritonavir, which is a highly potent P450 inhibitor, at steady
Eintrag öffnenMysildecard · 4.5 · Co-administration of the HIV protease inhibitor saquinavir, a CYP3A4 inhibitor, at steady state (1200 mg three
Eintrag öffnenMysildecard · 4.5 · Consistent with its known effects on the nitric oxide/cGMP pathway (see section 5.1), sildenafil was shown to
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