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Pemetrexed medac
Eintrag öffnenPemetrexed medac · 4.1 Therapeutic indications · 1
Eintrag öffnenPemetrexed medac · 4.3 Contraindications · 1
Eintrag öffnenPemetrexed medac · 4.3 · Breast-feeding (see section 4.6).
Eintrag öffnenPemetrexed medac · 4.3 · Concomitant yellow fever vaccine (see section 4.5).
Eintrag öffnenPemetrexed medac · 4.3 · Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Eintrag öffnenPemetrexed medac · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenPemetrexed medac · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenPemetrexed medac · 4.5 · Concomitant administration of pemetrexed with OAT3 (organic anion transporter 3) inhibitors (e.g. probenecid,
Eintrag öffnenPemetrexed medac · 4.5 · Concomitant use contraindicated: Yellow fever vaccine: risk of fatal generalised vaccine disease (see section
Eintrag öffnenPemetrexed medac · 4.5 · Concomitant use not recommended: Live attenuated vaccines (except yellow fever, for which concomitant use is c
Eintrag öffnenPemetrexed medac · 4.5 · Due to the increased thrombotic risk in patients with cancer, the use of anticoagulation treatment is frequent
Eintrag öffnenPemetrexed medac · 4.5 · In patients with mild to moderate renal insufficiency (creatinine clearance from 45 to 79 ml/min), the concomi
Eintrag öffnenPemetrexed medac · 4.5 · In patients with normal renal function (creatinine clearance ≥ 80 ml/min), high doses of non-steroidal anti-in
Eintrag öffnenPemetrexed medac · 4.5 · In the absence of data regarding potential interaction with NSAIDs having longer half-lives such as piroxicam
Eintrag öffnenPemetrexed medac · 4.5 · Interactions common to all cytotoxics
Eintrag öffnenPemetrexed medac · 4.5 · Pemetrexed is mainly eliminated unchanged renally by tubular secretion and to a lesser extent by glomerular fi
Eintrag öffnenPemetrexed medac · 4.5 · Pemetrexed undergoes limited hepatic metabolism. Results from in vitro studies with human liver microsomes ind
Eintrag öffnenPemetrexed medac · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenPemetrexed medac · 4.8 Undesirable effects · 1
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