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Eintrag öffnenPhesgo · 4.1 Therapeutic indications · 1
Eintrag öffnenPhesgo · 4.3 Contraindications · 1
Eintrag öffnenPhesgo · 4.3 · Hypersensitivity to the active substances or to any of the excipients listed in section 6.1.
Eintrag öffnenPhesgo · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenPhesgo · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenPhesgo · 4.5 · 8 any PK interaction between pertuzumab and any of these agents. The PK of pertuzumab in these studies was com
Eintrag öffnenPhesgo · 4.5 · By comparison of simulated serum trastuzumab concentrations after trastuzumab monotherapy (4 mg/kg loading/2 m
Eintrag öffnenPhesgo · 4.5 · Comparison of trastuzumab PK data from Study M77004 in which women with HER2-positive metastatic breast cancer
Eintrag öffnenPhesgo · 4.5 · Data from study JP16003, a single-arm study of trastuzumab (4 mg/kg intravenous loading dose and 2 mg/kg intra
Eintrag öffnenPhesgo · 4.5 · Effect of antineoplastic agents on trastuzumab pharmacokinetics
Eintrag öffnenPhesgo · 4.5 · Effect of trastuzumab on the pharmacokinetics of other antineoplastic agents
Eintrag öffnenPhesgo · 4.5 · Five studies evaluated the effects of pertuzumab on the PK of co-administered cytotoxic agents, docetaxel, pac
Eintrag öffnenPhesgo · 4.5 · No PK interactions were observed between pertuzumab and trastuzumab, or between pertuzumab and docetaxel in a
Eintrag öffnenPhesgo · 4.5 · No formal drug interaction studies have been performed.
Eintrag öffnenPhesgo · 4.5 · No formal drug interaction studies have been performed. Clinically significant interactions between trastuzuma
Eintrag öffnenPhesgo · 4.5 · PK data from Study H4613g/GO01305 in patients with metastatic or locally advanced inoperable HER2-positive can
Eintrag öffnenPhesgo · 4.5 · PK data from studies BO15935 and M77004 in women with HER2-positive metastatic breast cancer suggested that ex
Eintrag öffnenPhesgo · 4.5 · Pertuzumab
Eintrag öffnenPhesgo · 4.5 · Pharmacokinetic data from Study H4613g/GO01305 suggested that carboplatin had no impact on the PK of trastuzum
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