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Praluent
Eintrag öffnenPraluent · 4.1 Therapeutic indications · 1
Eintrag öffnenPraluent · 4.3 Contraindications · 1
Eintrag öffnenPraluent · 4.3 · Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Eintrag öffnenPraluent · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenPraluent · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenPraluent · 4.5 · Effects of alirocumab on other medicinal products
Eintrag öffnenPraluent · 4.5 · Effects of other medicinal products on alirocumab
Eintrag öffnenPraluent · 4.5 · Since alirocumab is a biological medicinal product, no pharmacokinetic effects of alirocumab on other medicina
Eintrag öffnenPraluent · 4.5 · Statins and other lipid-modifying therapy are known to increase production of PCSK9, the protein targeted by a
Eintrag öffnenPraluent · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenPraluent · 4.8 Undesirable effects · 1
Eintrag öffnenPraluent · 4.8 · * including mainly oropharyngeal pain, rhinorrhea, sneezing ** including erythema/redness, itching, swelling,
Eintrag öffnenPraluent · 4.8 · 6 System organ class Common Rare Not known
Eintrag öffnenPraluent · 4.8 · Although adverse consequences of very low LDL-C were not identified in alirocumab trials, the long-term effect
Eintrag öffnenPraluent · 4.8 · Anti-drug antibody responses, including NAb, were low titer and did not appear to have a clinically meaningful
Eintrag öffnenPraluent · 4.8 · Description of selected adverse reactions
Eintrag öffnenPraluent · 4.8 · Elderly Although no safety issues were observed in patients over 75 years of age, data are limited in this age
Eintrag öffnenPraluent · 4.8 · Every 4 week dosing study
Eintrag öffnenPraluent · 4.8 · Frequencies for all adverse reactions identified from clinical trials have been calculated based on their inci
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