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Pravafenix
Eintrag öffnenPravafenix · 4.1 Therapeutic indications · 1
Eintrag öffnenPravafenix · 4.3 Contraindications · 1
Eintrag öffnenPravafenix · 4.3 · - Hypersensitivity to the active substances or to any of the excipients listed in section 6.1. - Severe hepati
Eintrag öffnenPravafenix · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenPravafenix · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenPravafenix · 4.5 · 6 Bile acid binding resins frequently reduce the absorption of medicinal products and when resins are being co
Eintrag öffnenPravafenix · 4.5 · Ciclosporin Concomitant administration of pravastatin and ciclosporin leads to an approximately 4 fold increas
Eintrag öffnenPravafenix · 4.5 · Ciclosporin Some severe cases of reversible renal function impairment have been reported during concomitant ad
Eintrag öffnenPravafenix · 4.5 · Food interaction Pravafenix must be taken with food, as food enhances the bioavailability of fenofibrate (see
Eintrag öffnenPravafenix · 4.5 · Fusidic acid The risk of myopathy including rhabdomyolysis may be increased by the concomitant administration
Eintrag öffnenPravafenix · 4.5 · Glecaprevir/pibrentasvir Concomitant use of pravastatin and glecaprevir/pibrentasvir may increase the plasma c
Eintrag öffnenPravafenix · 4.5 · Glitazones Some cases of reversible paradoxical reduction of HDL-cholesterol have been reported during concomi
Eintrag öffnenPravafenix · 4.5 · In all clinical trials, patients were instructed to take Pravafenix daily during the evening meal and dietary
Eintrag öffnenPravafenix · 4.5 · In one of two interaction studies with pravastatin and erythromycin a statistically significant increase in th
Eintrag öffnenPravafenix · 4.5 · Interactions relevant to fenofibrate Bile acid resin
Eintrag öffnenPravafenix · 4.5 · Interactions relevant to pravastatin Colestyramine/Colestipol Concomitant administration resulted in approxima
Eintrag öffnenPravafenix · 4.5 · Medicinal products metabolised by cytochrome P450 Pravastatin is not metabolised to a clinically significant e
Eintrag öffnenPravafenix · 4.5 · Oral anticoagulants Fenofibrate enhances oral anticoagulant effect and may increase risk of bleeding. It is re
Eintrag öffnenPravafenix · 4.5 · Other medicinal products In interaction studies, no statistically significant differences in bioavailability w
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