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Methylthioninium chloride Proveblue
Eintrag öffnenMethylthioninium chloride Proveblue · 4.1 Therapeutic indications · 1
Eintrag öffnenMethylthioninium chloride Proveblue · 4.3 Contraindications · 1
Eintrag öffnenMethylthioninium chloride Proveblue · 4.3 · • Hypersensitivity to the active substance, or to any other thiazine dyes • Patients with Glucose-6-phosphate
Eintrag öffnenMethylthioninium chloride Proveblue · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenMethylthioninium chloride Proveblue · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenMethylthioninium chloride Proveblue · 4.5 · In a drug interaction study, a single IV dose of 2 mg/kg Methylthioninium chloride Proveblue did not have a cl
Eintrag öffnenMethylthioninium chloride Proveblue · 4.5 · Methylthioninium chloride is a potent inhibitor of the transporters OCT2, MATE1 and MATE2-K. The clinical cons
Eintrag öffnenMethylthioninium chloride Proveblue · 4.5 · Methylthioninium chloride is a potent reversible inhibitor of monoamine oxidase (see section 4.4).
Eintrag öffnenMethylthioninium chloride Proveblue · 4.5 · Methylthioninium chloride is a substrate of P-glycoprotein (P-gp). The clinical consequences are considered li
Eintrag öffnenMethylthioninium chloride Proveblue · 4.5 · Methylthioninium chloride is an in vitro inducer of CYP1A2. This interaction is not considered clinically rele
Eintrag öffnenMethylthioninium chloride Proveblue · 4.5 · Methylthioninium chloride should be avoided in patients receiving medicinal products that enhance serotonergic
Eintrag öffnenMethylthioninium chloride Proveblue · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenMethylthioninium chloride Proveblue · 4.8 Undesirable effects · 1
Eintrag öffnenMethylthioninium chloride Proveblue · 4.8 · 6 System organ class Adverse reactions Frequency Blood and lymphatic system Methaemoglobinaemia, Not known dis
Eintrag öffnenMethylthioninium chloride Proveblue · 4.8 · Adverse reactions are the same as in adults (except hyperbilirubinaemia, reported in infants only).
Eintrag öffnenMethylthioninium chloride Proveblue · 4.8 · Intravenous injection of methylthioninium chloride has occasionally caused hypotension and cardiac arrhythmias
Eintrag öffnenMethylthioninium chloride Proveblue · 4.8 · Paediatric population
Eintrag öffnenMethylthioninium chloride Proveblue · 4.8 · Reporting of suspected adverse reactions
Eintrag öffnenMethylthioninium chloride Proveblue · 4.8 · Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows con
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