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Lenalidomid
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Eintrag öffnenRevlimid · 4.1 Therapeutic indications · 1
Eintrag öffnenRevlimid · 4.3 Contraindications · 1
Eintrag öffnenRevlimid · 4.3 · • Hypersensitivity to the active substance or to any of the excipients listed in section 6.1. • Women who are
Eintrag öffnenRevlimid · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenRevlimid · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenRevlimid · 4.5 · Dexamethasone Co-administration of single or multiple doses of dexamethasone (40 mg once daily) has no clinica
Eintrag öffnenRevlimid · 4.5 · Digoxin Concomitant administration with lenalidomide 10 mg once daily increased the plasma exposure of digoxin
Eintrag öffnenRevlimid · 4.5 · Erythropoietic agents, or other agents that may increase the risk of thrombosis, such as hormone replacement t
Eintrag öffnenRevlimid · 4.5 · Interactions with P-glycoprotein (P-gp) inhibitors In vitro, lenalidomide is a substrate of P-gp, but is not a
Eintrag öffnenRevlimid · 4.5 · Oral contraceptives No interaction study has been performed with oral contraceptives. Lenalidomide is not an e
Eintrag öffnenRevlimid · 4.5 · Statins There is an increased risk of rhabdomyolysis when statins are administered with lenalidomide, which ma
Eintrag öffnenRevlimid · 4.5 · Warfarin Co-administration of multiple 10 mg doses of lenalidomide had no effect on the single dose pharmacoki
Eintrag öffnenRevlimid · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenRevlimid · 4.8 Undesirable effects · 1
Eintrag öffnenRevlimid · 4.8 · 25 Newly diagnosed multiple myeloma patients who are not eligible for transplant receiving lenalidomide in com
Eintrag öffnenRevlimid · 4.8 · 26 Serious adverse reactions include: • Venous thromboembolism (deep vein thrombosis, pulmonary embolism) (see
Eintrag öffnenRevlimid · 4.8 · 27 Tabulated list of adverse reactions The adverse reactions observed in patients treated with lenalidomide ar
Eintrag öffnenRevlimid · 4.8 · 28 System Organ Class/Preferred All ADRs/Frequency Grade 3-4 ADRs/Frequency Term Very Common Common Diarrhoea,
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