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Eintrag öffnenRistaben · 4.1 Therapeutic indications · 1
Eintrag öffnenRistaben · 4.3 Contraindications · 1
Eintrag öffnenRistaben · 4.3 · Hypersensitivity to the active substance or to any of the excipients listed in section 6.1 (see sections 4.4 a
Eintrag öffnenRistaben · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenRistaben · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenRistaben · 4.5 · Ciclosporin: A study was conducted to assess the effect of ciclosporin, a potent inhibitor of p-glycoprotein,
Eintrag öffnenRistaben · 4.5 · Effects of other medicinal products on sitagliptin Clinical data described below suggest that the risk for cli
Eintrag öffnenRistaben · 4.5 · Effects of sitagliptin on other medicinal products Digoxin: Sitagliptin had a small effect on plasma digoxin c
Eintrag öffnenRistaben · 4.5 · In vitro data suggest that sitagliptin does not inhibit nor induce CYP450 isoenzymes. In clinical studies, sit
Eintrag öffnenRistaben · 4.5 · In vitro studies indicated that the primary enzyme responsible for the limited metabolism of sitagliptin is CY
Eintrag öffnenRistaben · 4.5 · In vitro transport studies showed that sitagliptin is a substrate for p-glycoprotein and organic anion transpo
Eintrag öffnenRistaben · 4.5 · Metformin: Co-administration of multiple twice-daily doses of 1,000 mg metformin with 50 mg sitagliptin did no
Eintrag öffnenRistaben · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenRistaben · 4.8 Undesirable effects · 1
Eintrag öffnenRistaben · 4.8 · 6 Adverse reaction Frequency of adverse reaction
Eintrag öffnenRistaben · 4.8 · 7 TECOS Cardiovascular Safety Study The Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS) incl
Eintrag öffnenRistaben · 4.8 · Adverse reaction Frequency of adverse reaction
Eintrag öffnenRistaben · 4.8 · Blood and lymphatic system disorders thrombocytopenia Rare
Eintrag öffnenRistaben · 4.8 · Description of selected adverse reactions In addition to the drug-related adverse experiences described above,
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