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Lyvdelzi (previously Seladelpar Gilead)
Eintrag öffnenLyvdelzi (previously Seladelpar Gilead) · 4.1 Therapeutic indications · 1
Eintrag öffnenLyvdelzi (previously Seladelpar Gilead) · 4.3 Contraindications · 1
Eintrag öffnenLyvdelzi (previously Seladelpar Gilead) · 4.3 · Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Eintrag öffnenLyvdelzi (previously Seladelpar Gilead) · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenLyvdelzi (previously Seladelpar Gilead) · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenLyvdelzi (previously Seladelpar Gilead) · 4.5 · 3 In a dedicated clinical drug interaction study, seladelpar area under the curve from zero to time infinity (
Eintrag öffnenLyvdelzi (previously Seladelpar Gilead) · 4.5 · Bile acid binding resins
Eintrag öffnenLyvdelzi (previously Seladelpar Gilead) · 4.5 · Bile acid binding resins such as cholestyramine, colestipol, or colesevelam, may reduce the absorption of othe
Eintrag öffnenLyvdelzi (previously Seladelpar Gilead) · 4.5 · CYP2C9 and CYP3A4 inhibitors
Eintrag öffnenLyvdelzi (previously Seladelpar Gilead) · 4.5 · CYP2C9 inducers and strong CYP3A4 inducers
Eintrag öffnenLyvdelzi (previously Seladelpar Gilead) · 4.5 · Concomitant administration of seladelpar with dual or multiple clinical inhibitors of drugs transporters inclu
Eintrag öffnenLyvdelzi (previously Seladelpar Gilead) · 4.5 · Concomitant administration of seladelpar with medicines that are CYP2C9 inducers and strong CYP3A4 inducers (e
Eintrag öffnenLyvdelzi (previously Seladelpar Gilead) · 4.5 · Concomitant administration of seladelpar with probenecid (an OAT1, OAT3 and OATP1B1-inhibitor) is not recommen
Eintrag öffnenLyvdelzi (previously Seladelpar Gilead) · 4.5 · Effect of other medicinal products on seladelpar
Eintrag öffnenLyvdelzi (previously Seladelpar Gilead) · 4.5 · In a dedicated clinical drug interaction study, seladelpar AUC0-inf increased by 2.1-fold and Cmax by 2.9-fold
Eintrag öffnenLyvdelzi (previously Seladelpar Gilead) · 4.5 · In a dedicated clinical drug interaction study, seladelpar AUC0-inf increased by 2.4-fold and Cmax by 1.4-fold
Eintrag öffnenLyvdelzi (previously Seladelpar Gilead) · 4.5 · Inhibitors of drug transporters
Eintrag öffnenLyvdelzi (previously Seladelpar Gilead) · 4.5 · Probenecid
Eintrag öffnenLyvdelzi (previously Seladelpar Gilead) · 4.5 · Seladelpar AUC0-inf decreased by approximately 44% and Cmax by 24% following administration of a single 10 mg
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