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Silodyx
Eintrag öffnenSilodyx · 4.1 Therapeutic indications · 1
Eintrag öffnenSilodyx · 4.3 Contraindications · 1
Eintrag öffnenSilodyx · 4.3 · Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Eintrag öffnenSilodyx · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenSilodyx · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenSilodyx · 4.5 · Alpha-blockers There is inadequate information about the safe use of silodosin in association with other α-adr
Eintrag öffnenSilodyx · 4.5 · Antihypertensives In the clinical study program, many patients were on concomitant antihypertensive therapy (m
Eintrag öffnenSilodyx · 4.5 · CYP3A4 inhibitors In an interaction study, a 3.7-fold increase in maximum silodosin plasma concentrations and
Eintrag öffnenSilodyx · 4.5 · Digoxin Steady state levels of digoxin, a substrate of P-glycoprotein, were not significantly affected by co-a
Eintrag öffnenSilodyx · 4.5 · PDE-5 inhibitors Minimal pharmacodynamic interactions have been observed between silodosin and maximum doses o
Eintrag öffnenSilodyx · 4.5 · Silodosin is metabolised extensively, mainly via CYP3A4, alcohol dehydrogenase and UGT2B7. Silodosin is also a
Eintrag öffnenSilodyx · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenSilodyx · 4.8 Undesirable effects · 1
Eintrag öffnenSilodyx · 4.8 · 5 System organ Very Common Uncommon Rare Very rare Not known class common
Eintrag öffnenSilodyx · 4.8 · Description of selected adverse reactions
Eintrag öffnenSilodyx · 4.8 · Immune system Allergic-type disorders reactions including facial swelling, swollen tongue and pharyngeal oedem
Eintrag öffnenSilodyx · 4.8 · Intraoperative Floppy Iris Syndrome (IFIS) IFIS has been reported during cataract surgery (see section 4.4).
Eintrag öffnenSilodyx · 4.8 · Orthostatic hypotension The incidence of orthostatic hypotension in placebo-controlled clinical studies was 1.
Eintrag öffnenSilodyx · 4.8 · Reporting of suspected adverse reactions Reporting suspected adverse reactions after authorisation of the medi
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