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Simbrinza
Eintrag öffnenSimbrinza · 4.1 Therapeutic indications · 1
Eintrag öffnenSimbrinza · 4.3 Contraindications · 1
Eintrag öffnenSimbrinza · 4.3 · Hypersensitivity to the active substance(s) or to any of the excipients listed in section 6.1. Hypersensitivit
Eintrag öffnenSimbrinza · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenSimbrinza · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenSimbrinza · 4.5 · Alpha adrenergic agonists (e.g. brimonidine tartrate), as a class, may reduce pulse and blood pressure. Follow
Eintrag öffnenSimbrinza · 4.5 · Brinzolamide is a carbonic anhydrase inhibitor and, although administered topically, is absorbed systemically.
Eintrag öffnenSimbrinza · 4.5 · Caution is advised due to the possibility of an additive or potentiating effect with CNS depressants (e.g. alc
Eintrag öffnenSimbrinza · 4.5 · Caution is advised when initiating (or changing the dose of) concomitant systemic medicinal products (irrespec
Eintrag öffnenSimbrinza · 4.5 · No data on the level of circulating catecholamines after SIMBRINZA administration are available. However, caut
Eintrag öffnenSimbrinza · 4.5 · No specific drug interaction studies have been performed with SIMBRINZA.
Eintrag öffnenSimbrinza · 4.5 · SIMBRINZA is contraindicated in patients receiving monoamine oxidase inhibitors and in patients on antidepress
Eintrag öffnenSimbrinza · 4.5 · The cytochrome P-450 isozymes responsible for metabolism of brinzolamide include CYP3A4 (main), CYP2A6, CYP2B6
Eintrag öffnenSimbrinza · 4.5 · There is a potential for an additive effect on the known systemic effects of carbonic anhydrase inhibition in
Eintrag öffnenSimbrinza · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenSimbrinza · 4.8 Undesirable effects · 1
Eintrag öffnenSimbrinza · 4.8 · 6 System Organ Adverse reactions Classification Infections and Uncommon: nasopharyngitis2, pharyngitis2, sinus
Eintrag öffnenSimbrinza · 4.8 · 7 General disorders and Uncommon: pain2, chest discomfort2, feeling abnormal2, feeling jittery 2, administrati
Eintrag öffnenSimbrinza · 4.8 · Adverse reactions commonly associated with the brimonidine component of SIMBRINZA include the development of o
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