Gezielt nachschlagen
Suche
Suche startet nach einer kurzen Eingabepause.
20 angezeigte Treffer · Seite 1, keine Gesamtzahl für „Spexotras“
Suchtreffer
Begriffe & Kennungen
Spexotras
Eintrag öffnenSpexotras · 4.1 Therapeutic indications · 1
Eintrag öffnenSpexotras · 4.3 Contraindications · 1
Eintrag öffnenSpexotras · 4.3 · Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Eintrag öffnenSpexotras · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenSpexotras · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenSpexotras · 4.5 · Also refer to the guidance for medicinal product interactions for dabrafenib found in sections 4.4 and 4.5 of
Eintrag öffnenSpexotras · 4.5 · As trametinib is metabolised predominantly via deacetylation mediated by hydrolytic enzymes (e.g. carboxyl-est
Eintrag öffnenSpexotras · 4.5 · Based on clinical data, no loss of efficacy of hormonal contraceptives is expected when co- administered with
Eintrag öffnenSpexotras · 4.5 · Based on in vitro and in vivo data, trametinib is unlikely to significantly affect the pharmacokinetics of oth
Eintrag öffnenSpexotras · 4.5 · Effect of other medicinal products on trametinib
Eintrag öffnenSpexotras · 4.5 · Effect of the excipient sulfobutylbetadex sodium on other oral medicinal products with low bioavailability and
Eintrag öffnenSpexotras · 4.5 · Effect of trametinib on other medicinal products
Eintrag öffnenSpexotras · 4.5 · Interaction studies have only been performed in adults.
Eintrag öffnenSpexotras · 4.5 · The trametinib oral solution contains 100 mg/ml of sulfobutylbetadex sodium which may have the potential to af
Eintrag öffnenSpexotras · 4.5 · Trametinib is an in vitro substrate of the efflux transporter P-gp. As it cannot be excluded that strong inhib
Eintrag öffnenSpexotras · 4.6 Fertility, pregnancy, and lactation · 1
Eintrag öffnenSpexotras · 4.8 Undesirable effects · 1
Eintrag öffnenSpexotras · 4.8 · 12 (5%). Long-term data on growth and skeletal maturation in paediatric patients are currently limited (see se
Eintrag öffnenSpexotras · 4.8 · 13 Gastrointestinal disorders Very common Abdominal pain*, constipation, diarrhoea, nausea, vomiting Common Pa
Eintrag öffnen