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Begriffe & Kennungen
Erlotinib Hydrochlorid
Eintrag öffnenTarceva
Eintrag öffnenTarceva · 4.1 Therapeutic indications · 1
Eintrag öffnenTarceva · 4.3 Contraindications · 1
Eintrag öffnenTarceva · 4.3 · Hypersensitivity to erlotinib or to any of the excipients listed in section 6.1.
Eintrag öffnenTarceva · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenTarceva · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenTarceva · 4.5 · Erlotinib and Capecitabine Capecitabine may increase erlotinib concentrations. When erlotinib was given in com
Eintrag öffnenTarceva · 4.5 · Erlotinib and Carboplatin/Paclitaxel Erlotinib increases platinum concentrations. In a clinical study, the con
Eintrag öffnenTarceva · 4.5 · Erlotinib and Gemcitabine In a Phase Ib study, there were no significant effects of gemcitabine on the pharmac
Eintrag öffnenTarceva · 4.5 · Erlotinib and P-glycoprotein inhibitors Erlotinib is a substrate for the P-glycoprotein active substance trans
Eintrag öffnenTarceva · 4.5 · Erlotinib and coumarin-derived anticoagulants Interaction with coumarin-derived anticoagulants including warfa
Eintrag öffnenTarceva · 4.5 · Erlotinib and medicinal products altering pH Erlotinib is characterised by a decrease in solubility at pH abov
Eintrag öffnenTarceva · 4.5 · Erlotinib and other CYP substrates Erlotinib is a potent inhibitor of CYP1A1, and a moderate inhibitor of CYP3
Eintrag öffnenTarceva · 4.5 · Erlotinib and proteasome inhibitors Due to the working mechanism, proteasome inhibitors including bortezomib m
Eintrag öffnenTarceva · 4.5 · Erlotinib and smokers Results of a pharmacokinetic interaction study indicated a significant 2.8-, 1.5- and 9-
Eintrag öffnenTarceva · 4.5 · Erlotinib and statins The combination of Tarceva and a statin may increase the potential for statin-induced my
Eintrag öffnenTarceva · 4.5 · Erlotinib is metabolised in the liver by the hepatic cytochromes in humans, primarily CYP3A4 and to a lesser e
Eintrag öffnenTarceva · 4.5 · Interaction studies have only been performed in adults.
Eintrag öffnenTarceva · 4.5 · Potent inducers of CYP3A4 activity increase erlotinib metabolism and significantly decrease erlotinib plasma c
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