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Tevimbra
Eintrag öffnenTevimbra · 4.1 Therapeutic indications · 1
Eintrag öffnenTevimbra · 4.3 Contraindications · 1
Eintrag öffnenTevimbra · 4.3 · Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Eintrag öffnenTevimbra · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenTevimbra · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenTevimbra · 4.5 · The use of systemic corticosteroids and other immunosuppressants at baseline, before starting tislelizumab, ex
Eintrag öffnenTevimbra · 4.5 · Tislelizumab is a humanised monoclonal antibody, cleared from the circulation through catabolism. As such, for
Eintrag öffnenTevimbra · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenTevimbra · 4.8 Undesirable effects · 1
Eintrag öffnenTevimbra · 4.8 · 11 reactions (≥ 20%) were neutropenia (71.6%), anaemia (67.2%), thrombocytopenia (48.7%), nausea (43.3%), fati
Eintrag öffnenTevimbra · 4.8 · 12 Metabolism and nutrition disorders Hyperglycaemia11 Common Very common Hyponatraemia12 Common Very common H
Eintrag öffnenTevimbra · 4.8 · 13 General disorders and administration site conditions Fatigue32 Very common Very common Pyrexia33 Very commo
Eintrag öffnenTevimbra · 4.8 · 14 25 Rash includes PTs of rash, rash maculo-papular, eczema, rash erythematous, dermatitis, acute febrile neu
Eintrag öffnenTevimbra · 4.8 · 15 Tislelizumab was permanently discontinued in 0.3% of patients and tislelizumab treatment was interrupted in
Eintrag öffnenTevimbra · 4.8 · 16 Thyroiditis: In patients treated with tislelizumab as monotherapy, thyroiditis occurred in 1.1% of patients
Eintrag öffnenTevimbra · 4.8 · 17 Immune checkpoint inhibitor class effects There have been cases of the following adverse reactions reported
Eintrag öffnenTevimbra · 4.8 · 18 Reporting of suspected adverse reactions
Eintrag öffnenTevimbra · 4.8 · Adrenal insufficiency In patients treated with tislelizumab as monotherapy, adrenal insufficiency occurred in
Eintrag öffnenTevimbra · 4.8 · Adverse reactions reported in the pooled dataset for patients treated with Tevimbra monotherapy (N= 1952) and
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