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Tolvaptan Accord
Eintrag öffnenTolvaptan Accord · 4.1 Therapeutic indications · 1
Eintrag öffnenTolvaptan Accord · 4.3 Contraindications · 1
Eintrag öffnenTolvaptan Accord · 4.3 · 3 • Hypersensitivity to the active substance or to any of the excipients listed in section 6.1 or to benzazepi
Eintrag öffnenTolvaptan Accord · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenTolvaptan Accord · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenTolvaptan Accord · 4.5 · 6 lovastatin by 1.3-fold to 1.5-fold. Even though this increase has no clinical relevance, it indicates tolvap
Eintrag öffnenTolvaptan Accord · 4.5 · BCRP and OCT1 Co-administration of tolvaptan (90 mg) with rosuvastatin (5 mg), a BCRP substrate, increased ros
Eintrag öffnenTolvaptan Accord · 4.5 · CYP3A4 inducers
Eintrag öffnenTolvaptan Accord · 4.5 · CYP3A4 inhibitors
Eintrag öffnenTolvaptan Accord · 4.5 · CYP3A4 substrates
Eintrag öffnenTolvaptan Accord · 4.5 · Co-administration with other treatments for hyponatremia and medicinal products that increase serum sodium con
Eintrag öffnenTolvaptan Accord · 4.5 · Co-administration with vasopressin analogues
Eintrag öffnenTolvaptan Accord · 4.5 · Diuretics
Eintrag öffnenTolvaptan Accord · 4.5 · Effect of other medicinal products on the pharmacokinetics of tolvaptan
Eintrag öffnenTolvaptan Accord · 4.5 · Effect of tolvaptan on the pharmacokinetics of other products
Eintrag öffnenTolvaptan Accord · 4.5 · In addition to its renal aquaretic effect, tolvaptan is capable of blocking vascular vasopressin V2-receptors
Eintrag öffnenTolvaptan Accord · 4.5 · In healthy subjects, tolvaptan, a CYP3A4 substrate, had no effect on the plasma concentrations of some other C
Eintrag öffnenTolvaptan Accord · 4.5 · P-glycoprotein substrates In-vitro studies indicate that tolvaptan is a substrate and competitive inhibitor of
Eintrag öffnenTolvaptan Accord · 4.5 · There is no experience from controlled clinical trials with concomitant use of tolvaptan and other treatments
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