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Toviaz
Eintrag öffnenToviaz · 4.1 Therapeutic indications · 1
Eintrag öffnenToviaz · 4.3 Contraindications · 1
Eintrag öffnenToviaz · 4.3 · • Hypersensitivity to the active substance or to peanut or soya or to any of the excipients listed in section
Eintrag öffnenToviaz · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenToviaz · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenToviaz · 4.5 · 5 Oral contraceptives Fesoterodine does not impair the suppression of ovulation by oral hormonal contraception
Eintrag öffnenToviaz · 4.5 · CYP2D6 inhibitors The interaction with CYP2D6 inhibitors was not tested clinically. Mean Cmax and AUC of the a
Eintrag öffnenToviaz · 4.5 · CYP3A4 inducers Following induction of CYP3A4 by coadministration of rifampicin 600 mg once a day, Cmax and AU
Eintrag öffnenToviaz · 4.5 · CYP3A4 inhibitors
Eintrag öffnenToviaz · 4.5 · Fesoterodine may reduce the effect of medicinal products that stimulate the motility of the gastro-intestinal
Eintrag öffnenToviaz · 4.5 · Induction of CYP3A4 may lead to subtherapeutic plasma levels. Concomitant use with CYP3A4 inducers (e.g. carba
Eintrag öffnenToviaz · 4.5 · Moderate CYP3A4 inhibitors Following blockade of CYP3A4 by coadministration of the moderate CYP3A4 inhibitor f
Eintrag öffnenToviaz · 4.5 · Paediatric population Interaction studies have only been performed in adults.
Eintrag öffnenToviaz · 4.5 · Pharmacokinetic interactions In vitro data demonstrate that the active metabolite of fesoterodine does not inh
Eintrag öffnenToviaz · 4.5 · Pharmacological interactions Caution should be exercised in coadministration of fesoterodine with other antimu
Eintrag öffnenToviaz · 4.5 · Potent CYP3A4 inhibitors Following inhibition of CYP3A4 by co-administration of ketoconazole 200 mg twice dail
Eintrag öffnenToviaz · 4.5 · Warfarin A clinical study in healthy volunteers has shown that fesoterodine 8 mg once daily has no significant
Eintrag öffnenToviaz · 4.5 · Weak CYP3A4 inhibitors The effect of weak CYP3A4 inhibitors (e.g. cimetidine), was not examined; it is not exp
Eintrag öffnenToviaz · 4.6 Fertility, pregnancy and lactation · 1
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