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Eintrag öffnenTrisenox
Eintrag öffnenTrisenox · 4.1 Therapeutic indications · 1
Eintrag öffnenTrisenox · 4.3 Contraindications · 1
Eintrag öffnenTrisenox · 4.3 · Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Eintrag öffnenTrisenox · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenTrisenox · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenTrisenox · 4.5 · 6 may be at higher risk for torsade de pointes. Caution is advised when TRISENOX is co-administered with other
Eintrag öffnenTrisenox · 4.5 · Medicinal products known to cause QT/QTc interval prolongation, hypokalaemia or hypomagnesaemia QT/QTc prolong
Eintrag öffnenTrisenox · 4.5 · Medicinal products known to cause hepatotoxic effects Hepatotoxic effects may occur during the treatment with
Eintrag öffnenTrisenox · 4.5 · No formal assessments of pharmacokinetic interactions between TRISENOX and other therapeutic medicinal product
Eintrag öffnenTrisenox · 4.5 · Other antileukaemic medicinal products The influence of TRISENOX on the efficacy of other antileukaemic medici
Eintrag öffnenTrisenox · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenTrisenox · 4.8 Undesirable effects · 1
Eintrag öffnenTrisenox · 4.8 · 10 Haematological and gastrointestinal toxicity In newly diagnosed patients with low to intermediate risk APL,
Eintrag öffnenTrisenox · 4.8 · 7 In general, treatment-emergent adverse events tended to decrease over time, in relapsed/refractory APL patie
Eintrag öffnenTrisenox · 4.8 · 8 All grades Grades ≥ 3 Encephalopathy, Wernicke Not known Not known encephalopathy Eye disorders Vision blurr
Eintrag öffnenTrisenox · 4.8 · 9 *In the CALGB study C9710, 2 cases of grade ≥3 increased GGT were reported out of the 200 patients who recei
Eintrag öffnenTrisenox · 4.8 · Description of selected adverse reactions
Eintrag öffnenTrisenox · 4.8 · Differentiation syndrome During TRISENOX treatment, 14 of the 52 patients in the APL studies in the relapsed s
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