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Trizivir
Eintrag öffnenTrizivir · 4.1 Therapeutic indications · 1
Eintrag öffnenTrizivir · 4.3 Contraindications · 1
Eintrag öffnenTrizivir · 4.3 · Due to the active substance zidovudine, Trizivir is contraindicated in patients with abnormally low neutrophil
Eintrag öffnenTrizivir · 4.3 · Hypersensitivity to the active substances or to any of the excipients listed in section 6.1. See sections 4.4
Eintrag öffnenTrizivir · 4.3 · Patients with end-stage renal disease.
Eintrag öffnenTrizivir · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenTrizivir · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenTrizivir · 4.5 · 10 Drugs by Therapeutic Interaction Recommendation Area Geometric mean change concerning co- (%) administratio
Eintrag öffnenTrizivir · 4.5 · 11 Sorbitol solution (3.2 g, 10.2 g, Single dose lamivudine oral When possible, avoid chronic 13.4 g)/ Lamivud
Eintrag öffnenTrizivir · 4.5 · 8 Stavudine/Zidovudine In vitro antagonism of anti-HIV activity between stavudine and zidovudine could result
Eintrag öffnenTrizivir · 4.5 · 9 (600 mg once daily/200 mg (UGT induction) thrice daily) ANTICONVULSANTS Phenobarbital/Abacavir Interaction n
Eintrag öffnenTrizivir · 4.5 · ANTIFUNGALS Fluconazole/Abacavir Interaction not studied. As only limited data are Fluconazole/Lamivudine Inte
Eintrag öffnenTrizivir · 4.5 · Abacavir is metabolised by UDP-glucuronyltransferase (UGT) enzymes and alcohol dehydrogenase; co-administratio
Eintrag öffnenTrizivir · 4.5 · Abacavir, lamivudine and zidovudine are not significantly metabolised by cytochrome P450 enzymes (such as CYP
Eintrag öffnenTrizivir · 4.5 · Clinically significant interaction unlikely. Cimetidine eliminated only in part by renal organic cation transp
Eintrag öffnenTrizivir · 4.5 · Clinically significant interaction unlikely. Ranitidine eliminated only in part by renal organic cation transp
Eintrag öffnenTrizivir · 4.5 · Concomitant treatment, especially acute therapy, with potentially nephrotoxic or myelosuppressive medicinal pr
Eintrag öffnenTrizivir · 4.5 · Drugs by Therapeutic Area Interaction Recommendation Geometric mean change concerning co- (%) administration (
Eintrag öffnenTrizivir · 4.5 · Drugs by Therapeutic Area Interaction Recommendation Geometric mean change concerning co- (%) administration (
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