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Tigecyclin
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Eintrag öffnenTygacil · 4.1 Therapeutic indications · 1
Eintrag öffnenTygacil · 4.3 Contraindications · 1
Eintrag öffnenTygacil · 4.3 · Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Eintrag öffnenTygacil · 4.3 · Patients hypersensitive to tetracycline class antibiotics may be hypersensitive to tigecycline.
Eintrag öffnenTygacil · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenTygacil · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenTygacil · 4.5 · 5 (aPTT), the relevant coagulation tests should be closely monitored when tigecycline is co-administered with
Eintrag öffnenTygacil · 4.5 · Based on an in vitro study tigecycline is a P-gp substrate. Co-administration of P-gp inhibitors (e.g., ketoco
Eintrag öffnenTygacil · 4.5 · Concomitant administration of tigecycline and warfarin (25 mg single-dose) to healthy subjects resulted in a d
Eintrag öffnenTygacil · 4.5 · Concomitant use of tigecycline and calcineurin inhibitors such as tacrolimus or cyclosporine may lead to an in
Eintrag öffnenTygacil · 4.5 · Concurrent use of antibiotics with oral contraceptives may render oral contraceptives less effective.
Eintrag öffnenTygacil · 4.5 · Interaction studies have only been performed in adults.
Eintrag öffnenTygacil · 4.5 · Tigecycline in recommended dosage did not affect the rate or extent of absorption, or clearance of digoxin (0.
Eintrag öffnenTygacil · 4.5 · Tigecycline is not extensively metabolised. Therefore, clearance of tigecycline is not expected to be affected
Eintrag öffnenTygacil · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenTygacil · 4.8 Undesirable effects · 1
Eintrag öffnenTygacil · 4.8 · 7 System Very Common Uncommon Rare Frequency Organ Class Common ≥ 1/100 to ≥ 1/1,000 to ≥ 1/10,000 to not know
Eintrag öffnenTygacil · 4.8 · 8 Tigecycline may be associated with permanent tooth discolouration if used during tooth development (see sect
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