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Begriffe & Kennungen
Lapatinib
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Eintrag öffnenTyverb · 4.1 Therapeutic indications · 1
Eintrag öffnenTyverb · 4.3 Contraindications · 1
Eintrag öffnenTyverb · 4.3 · Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Eintrag öffnenTyverb · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenTyverb · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenTyverb · 4.5 · 7 increase in the AUC of digoxin. Caution should be exercised when dosing lapatinib concurrently with medicina
Eintrag öffnenTyverb · 4.5 · Co-administration of Tyverb with irinotecan (when administered as part of the FOLFIRI regimen) resulted in an
Eintrag öffnenTyverb · 4.5 · Co-administration of lapatinib with intravenous paclitaxel increased the exposure of paclitaxel by 23%, due to
Eintrag öffnenTyverb · 4.5 · Co-administration of lapatinib with intravenously administered docetaxel did not significantly affect the AUC
Eintrag öffnenTyverb · 4.5 · Concomitant administration of Tyverb with capecitabine, letrozole or trastuzumab did not meaningfully alter th
Eintrag öffnenTyverb · 4.5 · Effects of lapatinib on other medicinal products
Eintrag öffnenTyverb · 4.5 · Effects of other medicinal products on lapatinib
Eintrag öffnenTyverb · 4.5 · Grapefruit juice may inhibit CYP3A4 in the gut wall and increase the bioavailability of lapatinib and should t
Eintrag öffnenTyverb · 4.5 · In healthy volunteers receiving carbamazepine, a CYP3A4 inducer, at 100 mg twice daily for 3 days and 200 mg t
Eintrag öffnenTyverb · 4.5 · In healthy volunteers receiving ketoconazole, a strong CYP3A4 inhibitor, at 200 mg twice daily for 7 days, sys
Eintrag öffnenTyverb · 4.5 · Interactions with food and drink
Eintrag öffnenTyverb · 4.5 · Lapatinib inhibits CYP2C8 in vitro at clinically relevant concentrations. Co-administration of Tyverb with med
Eintrag öffnenTyverb · 4.5 · Lapatinib inhibits CYP3A4 in vitro at clinically relevant concentrations. Co-administration of Tyverb with ora
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