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Eintrag öffnenVegzelma · 4.1 Therapeutic indications · 1
Eintrag öffnenVegzelma · 4.3 Contraindications · 1
Eintrag öffnenVegzelma · 4.3 · ● Hypersensitivity to the active substance or to any of the excipients listed in section 6.1. ● Hypersensitivi
Eintrag öffnenVegzelma · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenVegzelma · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenVegzelma · 4.5 · 9 No interaction studies have been performed. EGFR monoclonal antibodies should not be administered for the tr
Eintrag öffnenVegzelma · 4.5 · Combination of bevacizumab and sunitinib malate In two clinical trials of metastatic renal cell carcinoma, mic
Eintrag öffnenVegzelma · 4.5 · Combination with platinum- or taxane-based therapies (see sections 4.4 and 4.8) Increased rates of severe neut
Eintrag öffnenVegzelma · 4.5 · EGFR monoclonal antibodies in combination with bevacizumab chemotherapy regimens
Eintrag öffnenVegzelma · 4.5 · Effect of antineoplastic agents on bevacizumab pharmacokinetics No clinically relevant interaction of co-admin
Eintrag öffnenVegzelma · 4.5 · Effect of bevacizumab on the pharmacokinetics of other antineoplastic agents No clinically relevant interactio
Eintrag öffnenVegzelma · 4.5 · MAHA is a haemolytic disorder which can present with red cell fragmentation, anaemia, and thrombocytopenia. In
Eintrag öffnenVegzelma · 4.5 · Radiotherapy The safety and efficacy of concomitant administration of radiotherapy and bevacizumab has not bee
Eintrag öffnenVegzelma · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenVegzelma · 4.8 Undesirable effects · 1
Eintrag öffnenVegzelma · 4.8 · 10 The most frequently observed adverse reactions across clinical trials in patients receiving bevacizumab wer
Eintrag öffnenVegzelma · 4.8 · 11 System organ Very common Common Uncommon Rare Very rare Frequency class not known Immune system Hypersensit
Eintrag öffnenVegzelma · 4.8 · 12 System organ Very common Common Uncommon Rare Very rare Frequency class not known urinary disorders Reprodu
Eintrag öffnenVegzelma · 4.8 · 13 System organ Very common Common Uncommon Rare Very Frequency not class rare known Vascular Hypertensiona,b
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