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Vosevi
Eintrag öffnenVosevi · 4.1 Therapeutic indications · 1
Eintrag öffnenVosevi · 4.3 Contraindications · 1
Eintrag öffnenVosevi · 4.3 · Concomitant use with ethinylestradiol-containing medicinal products such as combined oral contraceptives or co
Eintrag öffnenVosevi · 4.3 · Concomitant use with medicinal products that are strong P-glycoprotein (P-gp) and/or strong cytochrome P450 (C
Eintrag öffnenVosevi · 4.3 · Concomitant use with rosuvastatin or dabigatran etexilate (see section 4.5).
Eintrag öffnenVosevi · 4.3 · Hypersensitivity to the active substances or to any of the excipients listed in section 6.1.
Eintrag öffnenVosevi · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenVosevi · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenVosevi · 4.5 · (Increase in gastric pH decreases velpatasvir solubility)
Eintrag öffnenVosevi · 4.5 · (Increase in gastric pH decreases velpatasvir solubility) ANTIARRHYTHMICS Amiodarone Effect on amiodarone, vox
Eintrag öffnenVosevi · 4.5 · (Increase in gastric pH decreases velpatasvir solubility) Omeprazole Observed: (20 mg once daily) + Sofosbuvir
Eintrag öffnenVosevi · 4.5 · (Induction of P-gp and Expected: CYPs) ↔ Rifampicin Rifampicin (600 mg once Observed: daily) + sofosbuvir (400
Eintrag öffnenVosevi · 4.5 · (Inhibition of OATP1B and BCRP) Pravastatin Effect on sofosbuvir, velpatasvir and Pravastatin may be administe
Eintrag öffnenVosevi · 4.5 · (Inhibition of OATP1B) Other statins Effect on fluvastatin, lovastatin, pitavastatin Interactions cannot be ex
Eintrag öffnenVosevi · 4.5 · 10 Medicinal product by Effects on medicinal product levels. therapeutic areas/Possible Mean ratio (90% confid
Eintrag öffnenVosevi · 4.5 · 11 Medicinal product by Effects on medicinal product levels. therapeutic areas/Possible Mean ratio (90% confid
Eintrag öffnenVosevi · 4.5 · 12 Medicinal product by Effects on medicinal product levels. therapeutic areas/PossibleMean ratio (90% confide
Eintrag öffnenVosevi · 4.5 · 13 Medicinal product by Effects on medicinal product levels. therapeutic areas/Possible Mean ratio (90% confid
Eintrag öffnenVosevi · 4.5 · 14 Medicinal product by Effects on medicinal product levels. therapeutic areas/Possible Mean ratio (90% confid
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