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Xigduo
Eintrag öffnenXigduo · 4.1 Therapeutic indications · 1
Eintrag öffnenXigduo · 4.3 Contraindications · 1
Eintrag öffnenXigduo · 4.3 · - hypersensitivity to the active substances or to any of the excipients listed in section 6.1; - any type of a
Eintrag öffnenXigduo · 4.3 · Xigduo is contraindicated in patients with:
Eintrag öffnenXigduo · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenXigduo · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenXigduo · 4.5 · 7 Insulin and insulin secretagogues Insulin and insulin secretagogues, such as sulphonylureas, cause hypoglyca
Eintrag öffnenXigduo · 4.5 · 8 glycaemic control, dose adjustment within the recommended posology and changes in diabetic treatment should
Eintrag öffnenXigduo · 4.5 · Alcohol Alcohol intoxication is associated with an increased risk of lactic acidosis, particularly in the case
Eintrag öffnenXigduo · 4.5 · Coadministration of multiple doses of dapagliflozin and metformin does not meaningfully alter the pharmacokine
Eintrag öffnenXigduo · 4.5 · Combination requiring precautions for use Glucocorticoids (given by systemic and local routes), beta-2 agonist
Eintrag öffnenXigduo · 4.5 · Dapagliflozin Pharmacodynamic interactions Diuretics This medicinal product may add to the diuretic effect of
Eintrag öffnenXigduo · 4.5 · Effect of dapagliflozin on other medicinal products Dapagliflozin may increase renal lithium excretion and the
Eintrag öffnenXigduo · 4.5 · Effect of other medicinal products on dapagliflozin Interaction studies conducted in healthy subjects, using m
Eintrag öffnenXigduo · 4.5 · Following coadministration of dapagliflozin with mefenamic acid (an inhibitor of UGT1A9), a 55% increase in da
Eintrag öffnenXigduo · 4.5 · Following coadministration of dapagliflozin with rifampicin (an inducer of various active transporters and dru
Eintrag öffnenXigduo · 4.5 · In in vitro studies, dapagliflozin neither inhibited cytochrome P450 (CYP) 1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9
Eintrag öffnenXigduo · 4.5 · In interaction studies conducted in healthy subjects, using mainly a single-dose design, dapagliflozin did not
Eintrag öffnenXigduo · 4.5 · Insulin and insulin secretagogues Insulin and insulin secretagogues, such as sulphonylureas, cause hypoglycaem
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