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Zeposia
Eintrag öffnenZeposia · 4.1 Therapeutic indications · 1
Eintrag öffnenZeposia · 4.3 Contraindications · 1
Eintrag öffnenZeposia · 4.3 · • Hypersensitivity to the active substance or to any of the excipients listed in section 6.1. • Immunodeficien
Eintrag öffnenZeposia · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenZeposia · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenZeposia · 4.5 · 8 Vaccination
Eintrag öffnenZeposia · 4.5 · Anti-neoplastic, immunomodulatory or non-corticosteroid immunosuppressive therapies
Eintrag öffnenZeposia · 4.5 · Anti-neoplastic, immunomodulatory or non-corticosteroid immunosuppressive therapies should not be coadminister
Eintrag öffnenZeposia · 4.5 · Coadministration of ozanimod with ciclosporin, a strong BCRP inhibitor, had no effect on the exposure of ozani
Eintrag öffnenZeposia · 4.5 · During and for up to 3 months after treatment with ozanimod, vaccination may be less effective. The use of liv
Eintrag öffnenZeposia · 4.5 · Effect of inducers of CYP2C8 on ozanimod
Eintrag öffnenZeposia · 4.5 · Effect of inhibitors of CYP2C8 on ozanimod
Eintrag öffnenZeposia · 4.5 · Effect of inhibitors of monoamine oxidase (MAO) on ozanimod
Eintrag öffnenZeposia · 4.5 · Effect of inhibitors of the breast cancer resistance protein (BCRP) on ozanimod
Eintrag öffnenZeposia · 4.5 · Effects of ozanimod on medicinal products that slow heart rate or atrioventricular conduction (e.g., beta-bloc
Eintrag öffnenZeposia · 4.5 · In healthy subjects, a single dose of ozanimod 0.23 mg with steady state propranolol long acting 80 mg once da
Eintrag öffnenZeposia · 4.5 · The coadministration of gemfibrozil (a strong inhibitor of CYP2C8) 600 mg twice daily at steady state and a si
Eintrag öffnenZeposia · 4.5 · The coadministration of rifampicin (a strong inducer of CYP3A and P-gp, and a moderate inducer of CYP2C8) 600
Eintrag öffnenZeposia · 4.5 · The potential for clinical interaction with MAO inhibitors has not been studied. However, the coadministration
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