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Zykadia
Eintrag öffnenZykadia · 4.1 Therapeutic indications · 1
Eintrag öffnenZykadia · 4.1 Therapeutic indications · 2
Eintrag öffnenZykadia · 4.3 Contraindications · 1
Eintrag öffnenZykadia · 4.3 Contraindications · 2
Eintrag öffnenZykadia · 4.3 · Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Eintrag öffnenZykadia · 4.3 · Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
Eintrag öffnenZykadia · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenZykadia · 4.4 Special warnings and precautions for use · 2
Eintrag öffnenZykadia · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenZykadia · 4.5 Interaction with other medicinal products and other forms of interaction · 2
Eintrag öffnenZykadia · 4.5 · 33 nearest multiple of the 150 mg dose strength. After discontinuation of a strong CYP3A inhibitor, ceritinib
Eintrag öffnenZykadia · 4.5 · 34 Ceritinib has been classified in vivo as a weak CYP2C9 inhibitor. Co-administration of a single dose of war
Eintrag öffnenZykadia · 4.5 · 7 nefazodone), the dose of ceritinib should be reduced by approximately one third, rounded to the nearest mult
Eintrag öffnenZykadia · 4.5 · 8 Ceritinib has been classified in vivo as a weak CYP2C9 inhibitor. Co-administration of a single dose of warf
Eintrag öffnenZykadia · 4.5 · A risk for induction of other PXR regulated enzymes apart from CYP3A4 cannot be completely excluded. The effec
Eintrag öffnenZykadia · 4.5 · A risk for induction of other PXR regulated enzymes apart from CYP3A4 cannot be completely excluded. The effec
Eintrag öffnenZykadia · 4.5 · Agents that affect gastric pH Ceritinib demonstrates pH-dependent solubility and becomes poorly soluble as pH
Eintrag öffnenZykadia · 4.5 · Agents that affect gastric pH Ceritinib demonstrates pH-dependent solubility and becomes poorly soluble as pH
Eintrag öffnenZykadia · 4.5 · Agents that are substrates of transporters
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