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Begriffe zu „alectinib“: Alecensa · 4.3 · Hypersensitivity to alectinib or to any of the excipients listed in section 6.1.Alecensa · 4.5 · 6 combined exposure of alectinib and M4 was minor, reducing Cmax and AUCinf by 4 % and 18 %, respectively. BasAlecensa · 4.5 · Breast cancer resistance protein (BCRP) substrates In vitro, alectinib and M4 are inhibitors of the efflux traAlecensa · 4.5 · CYP substrates In vitro, alectinib and M4 show weak time-dependent inhibition of CYP3A4, and alectinib exhibitAlecensa · 4.5 · Effect of transporters on alectinib disposition M4 is a substrate of P-glycoprotein (P-gp). As alectinib inhib

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