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Doptelet · 4.5 · Concomitant use of avatrombopag with P-gp inhibitors resulted in alterations in exposure that were not clinica
Eintrag öffnenDoptelet · 4.5 · Concomitant use of avatrombopag with moderate or strong CYP3A4/5 and CYP2C9 dual inhibitors (e.g., fluconazole
Eintrag öffnenDoptelet · 4.5 · Medicinal products used in the treatment of ITP in combination with avatrombopag in clinical trials included c
Eintrag öffnenDoptelet · 4.5 · Reduce the starting dose of avatrombopag when used concomitantly with a moderate or strong dual inhibitor of C
Eintrag öffnenDoptelet · 4.5 · The decrease in avatrombopag exposure is not expected to have a clinically important effect on platelet counts
Eintrag öffnenDoptelet · 4.5 · The increase in avatrombopag exposure is not expected to have a clinically important effect on platelet counts
Eintrag öffnenDoptelet · 4.8 · The safety of avatrombopag in adult patients was evaluated in three controlled trials and one uncontrolled tri
Eintrag öffnenDoptelet · 4.8 · The safety of avatrombopag in paediatric patients ≥ 1 to < 18 years of age with persistent or chronic thromboc
Eintrag öffnenDoptelet · 4.8 · The safety of avatrombopag was evaluated in two randomised, double-blind, placebo-controlled trials, ADAPT-1 a
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