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18 angezeigte Treffer · Seite 1, keine Gesamtzahl für „bempedoic acid“
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Nilemdo · 4.5 · 5 If clinically relevant increased triglycerides or decreased HDL-C levels are detected, bempedoic acid or fib
Eintrag öffnenNilemdo · 4.5 · Bempedoic acid inhibits OAT2 in vitro, which may be the mechanism responsible for minor elevations in serum cr
Eintrag öffnenNilemdo · 4.5 · Effects of bempedoic acid on other medicinal products
Eintrag öffnenNilemdo · 4.5 · Effects of other medicinal products on bempedoic acid
Eintrag öffnenNilemdo · 4.5 · Fibrates Concomitant administration of fibrates with bempedoic acid resulted in increased triglycerides and de
Eintrag öffnenNilemdo · 4.5 · Other interactions studied Bempedoic acid had no effect on the pharmacokinetics or pharmacodynamics of metform
Eintrag öffnenNilemdo · 4.5 · Statins The pharmacokinetic interactions between bempedoic acid 180 mg and simvastatin 40 mg, atorvastatin 80
Eintrag öffnenNilemdo · 4.5 · Transporter-mediated drug interactions Bempedoic acid and its glucuronide weakly inhibit OATP1B1 and OATP1B3 a
Eintrag öffnenNilemdo · 4.5 · Transporter-mediated drug interactions In vitro drug interaction studies suggest bempedoic acid, as well as it
Eintrag öffnenNilemdo · 4.8 · Adverse reactions reported with bempedoic acid, based on incidence rates from phase 3 primary hyperlipidaemia
Eintrag öffnenNilemdo · 4.8 · Decreased haemoglobin Decreases in haemoglobin were observed in clinical trials with bempedoic acid. In the ph
Eintrag öffnenNilemdo · 4.8 · Effects on serum creatinine and blood urea nitrogen Bempedoic acid has been shown to increase serum creatinine
Eintrag öffnenNilemdo · 4.8 · Increased serum uric acid Increases in serum uric acid were observed in clinical trials with bempedoic acid po
Eintrag öffnenNilemdo · 4.8 · Of the 3 621 patients treated with bempedoic acid in the phase 3 primary hyperlipidemia studies, 2 098 (58%) w
Eintrag öffnenNilemdo · 4.8 · The most commonly reported adverse reactions with bempedoic acid during pivotal trials were hyperuricaemia (3.
Eintrag öffnenNilemdo · 4.8 · The observed elevations in serum creatinine may be associated with bempedoic acid inhibition of OAT2-dependent
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