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20 angezeigte Treffer · Seite 1, keine Gesamtzahl für „binimetinib“
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Braftovi · 4.5 · Effect of encorafenib on binimetinib While encorafenib is a relatively potent reversible inhibitor of UGT1A1,
Eintrag öffnenBraftovi · 4.8 · Hypertension Hypertension was reported when encorafenib was used in combination with binimetinib in melanoma a
Eintrag öffnenBraftovi · 4.8 · Left ventricular dysfunction LVD was reported when encorafenib is used in combination with binimetinib in mela
Eintrag öffnenBraftovi · 4.8 · The safety of encorafenib (300 mg orally once daily) in combination with binimetinib (45 mg orally twice daily
Eintrag öffnenBraftovi · 4.8 · The safety of encorafenib (450 mg orally once daily) in combination with binimetinib (45 mg orally twice daily
Eintrag öffnenBraftovi · 4.8 · Venous thromboembolism VTE was reported when encorafenib is used in combination with binimetinib in melanoma a
Eintrag öffnenBraftovi · 4.8 · When encorafenib was used at a dose of 300 mg once daily in combination with binimetinib 45 mg twice daily (Co
Eintrag öffnenMektovi · 4.5 · Binimetinib is a potential inducer of CYP1A2, and caution should be taken when it is used with sensitive subst
Eintrag öffnenMektovi · 4.5 · Binimetinib is a weak inhibitor of OAT3, and caution should be taken when it is used with sensitive substrates
Eintrag öffnenMektovi · 4.5 · Binimetinib is primarily metabolised through UGT1A1 mediated glucuronidation. The extent of drug interactions
Eintrag öffnenMektovi · 4.5 · Effects of binimetinib on other medicinal products
Eintrag öffnenMektovi · 4.5 · Effects of other medicinal products on binimetinib
Eintrag öffnenMektovi · 4.5 · While encorafenib is a relatively potent reversible inhibitor of UGT1A1, no differences in binimetinib exposur
Eintrag öffnenMektovi · 4.8 · Cutaneous malignancies CuSCC was reported when binimetinib was used in combination with encorafenib (see secti
Eintrag öffnenMektovi · 4.8 · Dermatologic reactions Dermatologic reactions may occur when binimetinib is used in combination with encorafen
Eintrag öffnenMektovi · 4.8 · Facial paresis Facial paresis was reported when binimetinib was used in combination with encorafenib (see sect
Eintrag öffnenMektovi · 4.8 · Palmar-plantar erythrodysaesthesia syndrome PPES can occur when binimetinib is used in combination with encora
Eintrag öffnenMektovi · 4.8 · Pancreatitis Pancreatitis was reported when binimetinib was used in combination with encorafenib (see section
Eintrag öffnenMektovi · 4.8 · Renal dysfunction Blood creatinine elevation and renal failure occurred when binimetinib was used in combinati
Eintrag öffnenMektovi · 4.8 · Table 3: Adverse reactions occurring in patients receiving binimetinib in combination with encorafenib at the
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