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Cinacalcet
Eintrag öffnenCinacalcet Accordpharma
Eintrag öffnenCinacalcet Accordpharma · 4.1 Therapeutic indications · 1
Eintrag öffnenCinacalcet Accordpharma · 4.3 Contraindications · 1
Eintrag öffnenCinacalcet Accordpharma · 4.3 · Hypersensitivity to the active substance or to any of the excipients listed in section 6.1. Hypocalcaemia (see
Eintrag öffnenCinacalcet Accordpharma · 4.4 Special warnings and precautions for use · 1
Eintrag öffnenCinacalcet Accordpharma · 4.5 Interaction with other medicinal products and other forms of interaction · 1
Eintrag öffnenCinacalcet Accordpharma · 4.5 · 7 Cinacalcet is metabolised in part by the enzyme CYP3A4. Co-administration of 200 mg bid ketoconazole, a stro
Eintrag öffnenCinacalcet Accordpharma · 4.5 · Calcium carbonate: Co-administration of calcium carbonate (single 1,500 mg dose) did not alter the pharmacokin
Eintrag öffnenCinacalcet Accordpharma · 4.5 · Concurrent administration of other medicinal products known to reduce serum calcium and cinacalcet may result
Eintrag öffnenCinacalcet Accordpharma · 4.5 · Desipramine: Concurrent administration of 90 mg cinacalcet once daily with 50 mg desipramine, a tricyclic anti
Eintrag öffnenCinacalcet Accordpharma · 4.5 · Dextromethorphan: Multiple doses of 50 mg cinacalcet increased the AUC of 30 mg dextromethorphan (metabolised
Eintrag öffnenCinacalcet Accordpharma · 4.5 · Effect of cinacalcet on other medicinal products
Eintrag öffnenCinacalcet Accordpharma · 4.5 · Effect of other medicinal products on cinacalcet
Eintrag öffnenCinacalcet Accordpharma · 4.5 · In vitro data indicate that cinacalcet is in part metabolised by CYP1A2. Smoking induces CYP1A2; the clearance
Eintrag öffnenCinacalcet Accordpharma · 4.5 · Medicinal products known to reduce serum calcium
Eintrag öffnenCinacalcet Accordpharma · 4.5 · Medicinal products metabolised by the enzyme P450 2D6 (CYP2D6): Cinacalcet is a strong inhibitor of CYP2D6. Do
Eintrag öffnenCinacalcet Accordpharma · 4.5 · Midazolam: Co-administration of cinacalcet (90 mg) with orally administered midazolam (2 mg), a CYP3A4 and CYP
Eintrag öffnenCinacalcet Accordpharma · 4.5 · Pantoprazole: Co-administration of pantoprazole (80 mg od) did not alter the pharmacokinetics of cinacalcet.
Eintrag öffnenCinacalcet Accordpharma · 4.5 · Sevelamer: Co-administration of sevelamer (2,400 mg tid) did not affect the pharmacokinetics of cinacalcet.
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