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15 angezeigte Treffer · Seite 1, keine Gesamtzahl für „dacomitinib“
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Vizimpro · 4.5 · Based on in vitro data, dacomitinib may have the potential to inhibit the activity of P-glycoprotein (P-gp) (i
Eintrag öffnenVizimpro · 4.5 · Co-administration of dacomitinib and CYP2D6 substrates
Eintrag öffnenVizimpro · 4.5 · Co-administration of dacomitinib with agents that increase gastric pH
Eintrag öffnenVizimpro · 4.5 · Co-administration of single 45 mg oral dose of dacomitinib increased the mean exposure (AUClast and Cmax) of d
Eintrag öffnenVizimpro · 4.5 · Effect of dacomitinib on drug transporters
Eintrag öffnenVizimpro · 4.5 · The aqueous solubility of dacomitinib is pH dependent, with low (acidic) pH resulting in higher solubility. Da
Eintrag öffnenVizimpro · 4.8 · 8 Table 3. Adverse reactions reported in dacomitinib clinical studies (N=255)
Eintrag öffnenVizimpro · 4.8 · Adverse reactions leading to dose reductions were reported in 52.2% of patients treated with dacomitinib. The
Eintrag öffnenVizimpro · 4.8 · Dacomitinib Gefitinib (N=227) (N=224) Adverse Reactionsa All Grades Grade 3 Grade 4 All Grades Grade 3 Grade 4
Eintrag öffnenVizimpro · 4.8 · Dacomitinib Gefitinib (N=227) (N=224) Adverse Reactionsa All Grades Grade 3 Grade 4 All Grades Grade 3 Grade 4
Eintrag öffnenVizimpro · 4.8 · Serious adverse reactions were reported in 6.7% of patients treated with dacomitinib. The most frequently (≥ 1
Eintrag öffnenVizimpro · 4.8 · Table 3. Adverse reactions reported in dacomitinib clinical studies (N=255)
Eintrag öffnenVizimpro · 4.8 · The most common (> 20%) adverse reactions in patients receiving dacomitinib were diarrhoea (88.6%), rash (79.2
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