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Darzalex · 4.5 · 8 Clinical pharmacokinetic assessments of daratumumab in combination with lenalidomide, pomalidomide, thalidom
Eintrag öffnenDarzalex · 4.5 · As an IgG1қ monoclonal antibody, renal excretion and hepatic enzyme-mediated metabolism of intact daratumumab
Eintrag öffnenDarzalex · 4.5 · Clinical pharmacokinetic assessments with daratumumab intravenous or subcutaneous formulations and lenalidomid
Eintrag öffnenDarzalex · 4.5 · Daratumumab binds to CD38 on RBCs and interferes with compatibility testing, including antibody screening and
Eintrag öffnenDarzalex · 4.5 · Daratumumab binds to CD38 on RBCs and interferes with compatibility testing, including antibody screening and
Eintrag öffnenDarzalex · 4.5 · Daratumumab may be detected on serum protein electrophoresis (SPE) and immunofixation (IFE) assays used for mo
Eintrag öffnenDarzalex · 4.5 · Daratumumab may be detected on serum protein electrophoresis (SPE) and immunofixation (IFE) assays used for mo
Eintrag öffnenDarzalex · 4.8 · 45 In patients with multiple myeloma receiving intravenous daratumumab combination therapy, the following were
Eintrag öffnenDarzalex · 4.8 · Elderly patients Of the 4553 patients who received daratumumab (n=1615 subcutaneous; n=2938 intravenous) at th
Eintrag öffnenDarzalex · 4.8 · In study MMY1001, patients receiving daratumumab combination treatment (n=97) were administered the first 16 m
Eintrag öffnenDarzalex · 4.8 · Infections In patients with multiple myeloma receiving daratumumab as monotherapy, the overall incidence of in
Eintrag öffnenDarzalex · 4.8 · The most frequent adverse reactions of any grade (≥ 20% patients) with daratumumab (either intravenous or subc
Eintrag öffnenDarzalex · 4.8 · The safety data also reflects exposure to intravenous daratumumab (16 mg/kg) in 2324 patients with multiple my
Eintrag öffnenKyprolis · 4.8 · In study 20160275 (see section 5.1), in which the administration of Kyprolis in combination with daratumumab a
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