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Begriffe zu „defibrotide“: Defitelio · 4.5 · Defibrotide does not inhibit or induce CYP450s (see section 5.2).Defitelio · 4.5 · Defibrotide has a profibrinolytic effect (see section 5.1) and this may potentially enhance the activity of anDefitelio · 4.5 · In a mouse model of thromboembolism, recombinant t-PA potentiated the antithrombotic effect of defibrotide wheDefitelio · 4.8 · In addition, although in the defibrotide studies in VOD there have been no reports of hypersensitivity, cases Defitelio · 4.8 · The safety evaluation of defibrotide is based on the safety pooled data set, which included patients who recei

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