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Trulicity · 4.5 · After coadministration of steady state digoxin with 2 consecutive 1.5 mg doses of dulaglutide, overall exposur
Eintrag öffnenTrulicity · 4.5 · Coadministration of 1.5 mg of dulaglutide with atorvastatin decreased Cmax and AUC(0-∞) up to 70 % and 21 %, r
Eintrag öffnenTrulicity · 4.5 · Coadministration of dulaglutide (1.5 mg) with an oral contraceptive (norgestimate 0.18 mg/ethinyl estradiol 0.
Eintrag öffnenTrulicity · 4.5 · Coadministration of multiple dulaglutide 1.5 mg doses with steady state lisinopril caused no clinically releva
Eintrag öffnenTrulicity · 4.5 · Dulaglutide delays gastric emptying and has the potential to impact the rate of absorption of concomitantly ad
Eintrag öffnenTrulicity · 4.5 · Following a first dose of 1 and 3 mg dulaglutide, paracetamol Cmax was reduced by 36 % and 50 %, respectively,
Eintrag öffnenTrulicity · 4.5 · Following coadministration of multiple 1.5 mg doses of dulaglutide with steady state metformin (immediate rele
Eintrag öffnenTrulicity · 4.5 · Following dulaglutide (1.5 mg) coadministration, S- and R-warfarin exposure and R-warfarin Cmax were unaffecte
Eintrag öffnenTrulicity · 4.5 · For patients receiving dulaglutide in combination with oral medicinal products with rapid gastrointestinal abs
Eintrag öffnenTrulicity · 4.5 · Sitagliptin can produce up to 80 % inhibition of DPP-4 over a 24-hour period. Dulaglutide (1.5 mg) coadministr
Eintrag öffnenTrulicity · 4.5 · Sitagliptin exposure was unaffected when coadministered with a single 1.5 mg dose of dulaglutide. Following co
Eintrag öffnenTrulicity · 4.8 · 10 and modified IgG4 parts of the dulaglutide molecule, together with high homology with native GLP-1 and nati
Eintrag öffnenTrulicity · 4.8 · 9 The incidences when dulaglutide 0.75 mg and 1.5 mg, respectively, were used in combination with prandial ins
Eintrag öffnenTrulicity · 4.8 · Dulaglutide doses of 3 mg and 4.5 mg The safety profile in patients treated with dulaglutide 3 mg and 4.5 mg o
Eintrag öffnenTrulicity · 4.8 · Hypoglycaemia When dulaglutide 0.75 mg and 1.5 mg were used as monotherapy or in combination with metformin al
Eintrag öffnenTrulicity · 4.8 · Immunogenicity In registration studies, treatment with dulaglutide was associated with a 1.6 % incidence of tr
Eintrag öffnenTrulicity · 4.8 · In a phase 3 study through to week 52, when dulaglutide 1.5 mg, 3 mg and 4.5 mg were used in combination with
Eintrag öffnenTrulicity · 4.8 · In a phase 3 study with 1.5 mg, 3 mg and 4.5 mg dulaglutide doses respectively, cumulative reporting of gastro
Eintrag öffnenTrulicity · 4.8 · In a phase 3 study with 1.5 mg, 3 mg and 4.5 mg dulaglutide doses, the incidence of discontinuation due to adv
Eintrag öffnenTrulicity · 4.8 · In a phase 3 study with 1.5 mg, 3 mg and 4.5 mg dulaglutide doses, the incidence of first-degree AV block was
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