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Casgevy · 4.8 · In study 111, the median (min, max) time to neutrophil engraftment in patients with TDT was 29 (12, 56) days (
Eintrag öffnenCasgevy · 4.8 · In study 111, the median (min, max) time to platelet engraftment in patients with TDT was 44 (20, 200) days (n
Eintrag öffnenCasgevy · 4.8 · In study 121, the median (min, max) time to neutrophil engraftment in patients with SCD was 27 (15, 40) days (
Eintrag öffnenCasgevy · 4.8 · In study 121, the median (min, max) time to platelet engraftment for patients with SCD was 35 (23, 126) days (
Eintrag öffnenCasgevy · 4.8 · Neutrophil engraftment
Eintrag öffnenCasgevy · 4.8 · Neutrophil engraftment was defined as 3 consecutive measurements of absolute neutrophil count (ANC) ≥ 500 cell
Eintrag öffnenCasgevy · 4.8 · Platelet engraftment
Eintrag öffnenCasgevy · 4.8 · Platelet engraftment was defined as 3 consecutive measurements of platelet counts ≥ 20 × 109/L in patients wit
Eintrag öffnenCasgevy · 4.8 · There was no association observed between bleeding events and time to platelet engraftment after Casgevy treat
Eintrag öffnenCasgevy · 4.8 · There was no association observed between infections and time to neutrophil engraftment.
Eintrag öffnenZemcelpro · 4.5 · Use of ATG is not recommended as part of the conditioning regimen and prior to engraftment.
Eintrag öffnenZemcelpro · 4.8 · Engraftment syndrome Engraftment syndrome was reported in 11.2% (13/116) of patients transplanted with Zemcelp
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