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Entrectinib
Eintrag öffnenRozlytrek · 4.5 · 10 Effect of entrectinib on other transporter substrates In vitro data indicate that entrectinib has weak inhi
Eintrag öffnenRozlytrek · 4.5 · 41 Effect of CYP3A or P-gp inducers on entrectinib Co-administration of multiple oral doses of rifampin, a str
Eintrag öffnenRozlytrek · 4.5 · Although, a marked effect of inhibitory P-gp medicinal products on entrectinib pharmacokinetics is not expecte
Eintrag öffnenRozlytrek · 4.5 · Although, a marked effect of inhibitory P-gp medicinal products on entrectinib pharmacokinetics is not expecte
Eintrag öffnenRozlytrek · 4.5 · Based on in vitro data, CYP3A4 is the predominant enzyme mediating the metabolism of entrectinib and formation
Eintrag öffnenRozlytrek · 4.5 · Based on in vitro data, CYP3A4 is the predominant enzyme mediating the metabolism of entrectinib and formation
Eintrag öffnenRozlytrek · 4.5 · Co-administration of a single 600 mg dose of entrectinib with digoxin (a sensitive P-gp substrate) increased d
Eintrag öffnenRozlytrek · 4.5 · Co-administration of a single 600 mg dose of entrectinib with digoxin (a sensitive P-gp substrate) increased d
Eintrag öffnenRozlytrek · 4.5 · Co-administration of entrectinib with CYP3A/P-gp inducers (including, but not limited to, carbamazepine, pheno
Eintrag öffnenRozlytrek · 4.5 · Co-administration of entrectinib with CYP3A/P-gp inducers (including, but not limited to, carbamazepine, pheno
Eintrag öffnenRozlytrek · 4.5 · Effect of CYP3A or P-gp inducers on entrectinib Co-administration of multiple oral doses of rifampin, a strong
Eintrag öffnenRozlytrek · 4.5 · Effect of CYP3A or P-gp inhibitors on entrectinib Co-administration of itraconazole, a strong CYP3A4 inhibitor
Eintrag öffnenRozlytrek · 4.5 · Effect of CYP3A or P-gp inhibitors on entrectinib Co-administration of itraconazole, a strong CYP3A4 inhibitor
Eintrag öffnenRozlytrek · 4.5 · Effect of entrectinib on BCRP substrates Inhibition of BCRP was observed in in vitro studies. The clinical rel
Eintrag öffnenRozlytrek · 4.5 · Effect of entrectinib on BCRP substrates Inhibition of BCRP was observed in in vitro studies. The clinical rel
Eintrag öffnenRozlytrek · 4.5 · Effect of entrectinib on CYP substrates Entrectinib is a weak inhibitor of CYP3A4. Co-administration of entrec
Eintrag öffnenRozlytrek · 4.5 · Effect of entrectinib on CYP substrates Entrectinib is a weak inhibitor of CYP3A4. Co-administration of entrec
Eintrag öffnenRozlytrek · 4.5 · Effect of entrectinib on P-gp substrates In vitro data suggest that entrectinib has inhibitory potential towar
Eintrag öffnenRozlytrek · 4.5 · Effect of entrectinib on P-gp substrates In vitro data suggest that entrectinib has inhibitory potential towar
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