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12 angezeigte Treffer · Seite 1, keine Gesamtzahl für „eribulin“
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Eribulin
Eintrag öffnenHalaven · 4.5 · At relevant clinical concentrations, eribulin did not inhibit BCRP, OCT1, OCT2, OAT1, OAT3, OATP1B1 and OATP1B
Eintrag öffnenHalaven · 4.5 · Effects of eribulin on the pharmacokinetics of other medicines
Eintrag öffnenHalaven · 4.5 · Eribulin does not inhibit the CYP enzymes CYP1A2, 2B6, 2C8, 2C9, 2C19, 2D6 or 2E1 at relevant clinical concent
Eintrag öffnenHalaven · 4.5 · Eribulin is mainly (up to 70%) eliminated through biliary excretion. The transport protein involved in this pr
Eintrag öffnenHalaven · 4.5 · In vitro data indicate that eribulin is a mild inhibitor of the important drug metabolising enzyme CYP3A4. No
Eintrag öffnenHalaven · 4.5 · No drug-drug interactions are expected with CYP3A4 inhibitors and inducers. Eribulin exposure (AUC and Cmax) w
Eintrag öffnenHalaven · 4.8 · Elderly population Of the 1559 breast cancer patients treated with the recommended dose of eribulin, 283 patie
Eintrag öffnenHalaven · 4.8 · Hepatotoxicity In some patients with normal/abnormal liver enzymes prior treatment with eribulin, increased le
Eintrag öffnenHalaven · 4.8 · The safety of eribulin monotherapy was evaluated in 43 paediatric patients who received up to 1.58 mg/m2 on Da
Eintrag öffnenHalaven · 4.8 · The safety profile of eribulin as monotherapy or in combination with irinotecan hydrochloride in this paediatr
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