Gezielt nachschlagen
Suche
Suche startet nach einer kurzen Eingabepause.
20 angezeigte Treffer · Seite 1, keine Gesamtzahl für „lapatinib“
Suchtreffer
Begriffe & Kennungen
Lapatinib
Eintrag öffnenLumykras · 4.5 · When LUMYKRAS is co-administered with a BCRP substrate, including but not limited to lapatinib, methotrexate,
Eintrag öffnenTyverb · 4.5 · 7 increase in the AUC of digoxin. Caution should be exercised when dosing lapatinib concurrently with medicina
Eintrag öffnenTyverb · 4.5 · Co-administration of lapatinib with intravenous paclitaxel increased the exposure of paclitaxel by 23%, due to
Eintrag öffnenTyverb · 4.5 · Co-administration of lapatinib with intravenously administered docetaxel did not significantly affect the AUC
Eintrag öffnenTyverb · 4.5 · Effects of lapatinib on other medicinal products
Eintrag öffnenTyverb · 4.5 · Effects of other medicinal products on lapatinib
Eintrag öffnenTyverb · 4.5 · Grapefruit juice may inhibit CYP3A4 in the gut wall and increase the bioavailability of lapatinib and should t
Eintrag öffnenTyverb · 4.5 · Lapatinib inhibits CYP2C8 in vitro at clinically relevant concentrations. Co-administration of Tyverb with med
Eintrag öffnenTyverb · 4.5 · Lapatinib inhibits CYP3A4 in vitro at clinically relevant concentrations. Co-administration of Tyverb with ora
Eintrag öffnenTyverb · 4.5 · Lapatinib inhibits the transport protein Pgp in vitro at clinically relevant concentrations. Co-administration
Eintrag öffnenTyverb · 4.5 · Lapatinib inhibits the transport proteins BCRP and OATP1B1 in vitro. The clinical relevance of this effect has
Eintrag öffnenTyverb · 4.5 · Lapatinib is a substrate for the transport proteins Pgp and BCRP. Inhibitors (ketoconazole, itraconazole, quin
Eintrag öffnenTyverb · 4.5 · Lapatinib is predominantly metabolised by CYP3A (see section 5.2).
Eintrag öffnenTyverb · 4.5 · The bioavailability of lapatinib is increased up to about 4 times by food, depending on e.g. the fat content i
Eintrag öffnenTyverb · 4.5 · The solubility of lapatinib is pH-dependent. Concomitant treatment with substances that increase gastric pH sh
Eintrag öffnenTyverb · 4.8 · Diarrhoea occurred in approximately 65 % of patients who received lapatinib in combination with capecitabine,
Eintrag öffnenTyverb · 4.8 · No additional adverse reactions were reported to be associated with lapatinib in combination with trastuzumab.
Eintrag öffnenTyverb · 4.8 · Rash occurred in approximately 28 % of patients who received lapatinib in combination with capecitabine, in 45
Eintrag öffnenTyverb · 4.8 · The following adverse reactions have been reported to have a causal association with lapatinib alone or lapati
Eintrag öffnen