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Akeega · 4.5 · Effects of niraparib or abiraterone acetate on other medicinal products CYP2D6 substrates Abiraterone is an in
Eintrag öffnenAkeega · 4.5 · Effects of other medicinal products on niraparib or abiraterone acetate CYP3A4 inducers and inhibitors Abirate
Eintrag öffnenAkeega · 4.8 · Hepatotoxicity The overall incidence of hepatotoxicity was similar for the niraparib plus AAP (13.6%) and plac
Eintrag öffnenAkeega · 4.8 · The incidence of cardiac failure (grouped term) was 4.7% in the niraparib plus AAP arm vs 1.8% in placebo plus
Eintrag öffnenAkeega · 4.8 · The incidence of ischaemic heart disease (grouped term) was 5.4% in the niraparib plus AAP arm vs 5.0% in the
Eintrag öffnenZejula · 4.5 · Effect of niraparib on other medicinal products
Eintrag öffnenZejula · 4.5 · Effect of niraparib on other medicinal products
Eintrag öffnenZejula · 4.5 · In vitro, niraparib is an inhibitor of BCRP. A clinically relevant interaction with BCRP substrates cannot be
Eintrag öffnenZejula · 4.5 · In vitro, niraparib is an inhibitor of BCRP. A clinically relevant interaction with BCRP substrates cannot be
Eintrag öffnenZejula · 4.5 · Induction of CYP1A2 In vitro, niraparib induces CYP1A2. Therefore, caution is recommended when niraparib is co
Eintrag öffnenZejula · 4.5 · Induction of CYP1A2 In vitro, niraparib induces CYP1A2. Therefore, caution is recommended when niraparib is co
Eintrag öffnenZejula · 4.5 · Niraparib is an inhibitor of MATE1 and -2K in vitro. Plasma concentrations of metformin may increase when conc
Eintrag öffnenZejula · 4.5 · Niraparib is an inhibitor of MATE1 and -2K in vitro. Plasma concentrations of metformin may increase when conc
Eintrag öffnenZejula · 4.5 · No clinical drug interaction studies have been performed with niraparib.
Eintrag öffnenZejula · 4.5 · No clinical drug interaction studies have been performed with niraparib.
Eintrag öffnenZejula · 4.5 · The combination of niraparib with vaccines or immunosuppressant agents has not been studied.
Eintrag öffnenZejula · 4.5 · The combination of niraparib with vaccines or immunosuppressant agents has not been studied.
Eintrag öffnenZejula · 4.5 · The data on niraparib in combination with cytotoxic medicinal products are limited. Therefore, caution should
Eintrag öffnenZejula · 4.5 · The data on niraparib in combination with cytotoxic medicinal products are limited. Therefore, caution should
Eintrag öffnenabiraterone acetate;niraparib (tosilate monohydrate)
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