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Oncaspar · 4.5 · An indirect interaction cannot be ruled out between pegaspargase and oral contraceptives due to pegaspargase h
Eintrag öffnenOncaspar · 4.5 · Immediately preceding or simultaneous treatment with vincristine can increase the toxicity of pegaspargase. Ad
Eintrag öffnenOncaspar · 4.5 · In addition, by inhibiting protein synthesis and cell division, pegaspargase can disturb the mechanism of acti
Eintrag öffnenOncaspar · 4.5 · Pegaspargase can interfere with metabolism and clearance of other medicinal products, based on its effects on
Eintrag öffnenOncaspar · 4.5 · Pegaspargase may increase the risk of glucocorticoid-induced osteonecrosis in children and adolescents when bo
Eintrag öffnenOncaspar · 4.5 · The decrease in serum proteins caused by pegaspargase can increase the toxicity of other medicinal products th
Eintrag öffnenOncaspar · 4.5 · When glucocorticoids (e.g., prednisone) and pegaspargase are given at the same time, alterations in coagulatio
Eintrag öffnenOncaspar · 4.8 · Immune system disorders Specific antibodies to pegaspargase have been detected; uncommonly they were associate
Eintrag öffnenOncaspar · 4.8 · Not known: Blood urea increased, anti-pegaspargase antibodies, platelet count decreased, hyperammonaemia
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