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Fycompa · 4.5 · Effect of cytochrome P450 inducers on perampanel pharmacokinetics
Eintrag öffnenFycompa · 4.5 · Effect of cytochrome P450 inducers on perampanel pharmacokinetics
Eintrag öffnenFycompa · 4.5 · Effect of cytochrome P450 inhibitors on perampanel pharmacokinetics
Eintrag öffnenFycompa · 4.5 · Effect of cytochrome P450 inhibitors on perampanel pharmacokinetics
Eintrag öffnenFycompa · 4.5 · Effect of perampanel on CYP3A substrates
Eintrag öffnenFycompa · 4.5 · Effect of perampanel on CYP3A substrates
Eintrag öffnenFycompa · 4.5 · In healthy subjects, the CYP3A4 inhibitor ketoconazole (400 mg once daily for 10 days) increased perampanel AU
Eintrag öffnenFycompa · 4.5 · In healthy subjects, the CYP3A4 inhibitor ketoconazole (400 mg once daily for 10 days) increased perampanel AU
Eintrag öffnenFycompa · 4.5 · Perampanel is dosed to clinical effect regardless of other AEDs.
Eintrag öffnenFycompa · 4.5 · Perampanel is dosed to clinical effect regardless of other AEDs.
Eintrag öffnenFycompa · 4.5 · Perampanel was found to decrease the clearance of oxcarbazepine by 26%. Oxcarbazepine is rapidly metabolised b
Eintrag öffnenFycompa · 4.5 · Perampanel was found to decrease the clearance of oxcarbazepine by 26%. Oxcarbazepine is rapidly metabolised b
Eintrag öffnenFycompa · 4.5 · Strong inducers of cytochrome P450, such as rifampicin and hypericum, are expected to decrease perampanel conc
Eintrag öffnenFycompa · 4.5 · Strong inducers of cytochrome P450, such as rifampicin and hypericum, are expected to decrease perampanel conc
Eintrag öffnenFycompa · 4.5 · The effects of perampanel on tasks involving alertness and vigilance such as driving ability were additive or
Eintrag öffnenFycompa · 4.5 · The effects of perampanel on tasks involving alertness and vigilance such as driving ability were additive or
Eintrag öffnenFycompa · 4.8 · 11 in the total perampanel group and greater than placebo) leading to discontinuation were dizziness and somno
Eintrag öffnenFycompa · 4.8 · Available data in children did not suggest any clinically significant effects of perampanel on growth and deve
Eintrag öffnenFycompa · 4.8 · Available data in children did not suggest any clinically significant effects of perampanel on growth and deve
Eintrag öffnenFycompa · 4.8 · Based on the clinical trial database of 180 paediatric patients exposed to perampanel from a multicentre, open
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