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Orgovyx

relugolix · L02BX

Ryeqo

relugolix;norethisterone acetate;estradiol hemihydrate · H01CC54

Orgovyx · 4.5 · *: Upon co-administration of azithromycin and relugolix, relugolix exposure increases up to 5-fold were observ

Orgovyx · 4.5 · 11 Relugolix dose Drug dose Change in Change in Recommendation regimen regimen drug AUC0- drug Cmax inf

Orgovyx · 4.5 · 5 Table 1. Effect of co-administered medicinal products on relugolix exposure (Cmax, AUC0- inf) and recommenda

Orgovyx · 4.5 · 9 to 266 days in the phase 3 study, plasma relugolix trough concentrations did not change to a clinically sign

Orgovyx · 4.5 · Based on limited data (n=20) in men who received a 120 mg dose of relugolix and 80 to 160 mg doses of enzaluta

Orgovyx · 4.5 · Co-administration of Orgovyx and oral P-gp inhibitors is not recommended. Relugolix is a P-gp substrate (see s