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Begriffe zu „rucaparib“: Rubraca · 4.5 · 6 CYP3A substrates Rucaparib increased midazolam Cmax by 1.13 fold (90% CI: 0.95 to 1.36) and AUCinf by 1.38 fRubraca · 4.5 · BCRP substrates Rucaparib increased rosuvastatin Cmax by 1.29 fold (90% CI: 1.07 to 1.55) and AUCinf by 1.35 fRubraca · 4.5 · CYP1A2 substrates Rucaparib showed no effect on Cmax of caffeine while moderately increasing AUCinf of caffeinRubraca · 4.5 · CYP2C19 substrates Rucaparib increased omeprazole Cmax by 1.09 fold (90% CI: 0.93 to 1.27) and AUCinf by 1.55 Rubraca · 4.5 · CYP2C9 substrates Rucaparib increased S-warfarin Cmax by 1.05 fold (90% CI: 0.99 to 1.12) and AUC0-96 h by 1.4

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