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Begriffe zu „siponimod“: Mayzent · 4.5 · CYP2C9 and CYP3A4 inducers Siponimod may be combined with most types of CYP2C9 and CYP3A4 inducers. However, bMayzent · 4.5 · CYP2C9 inhibitors Concomitant use of siponimod and medicinal products that cause moderate or strong CYP2C9 inhMayzent · 4.5 · Caution should be exercised when siponimod is initiated in patients receiving beta blockers due to the additivMayzent · 4.5 · Co-administration with siponimod did not reveal clinically relevant effects on the pharmacokinetics and pharmaMayzent · 4.5 · Cytochrome P450 (CYP2C9) is the major metabolising enzyme for siponimod, accounting for 79.5% of metabolism in

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