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20 angezeigte Treffer · Seite 1, keine Gesamtzahl für „temsirolimus“
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Torisel · 4.3 · Hypersensitivity to temsirolimus, its metabolites (including sirolimus), polysorbate 80, or to any of the exci
Eintrag öffnenTorisel · 4.3 · Use of temsirolimus in patients with MCL with moderate or severe hepatic impairment.
Eintrag öffnenTorisel · 4.5 · Co-administration of temsirolimus 5 mg with ketoconazole, a potent CYP3A4 inhibitor, had no significant effect
Eintrag öffnenTorisel · 4.5 · Co-administration of temsirolimus with rifampicin, a potent CYP3A4/5 inducer, had no significant effect on tem
Eintrag öffnenTorisel · 4.5 · Concomitant use of temsirolimus with sunitinib
Eintrag öffnenTorisel · 4.5 · In an in vitro study, temsirolimus inhibited the transport of P-glycoprotein (P-gp) substrates with an IC50 va
Eintrag öffnenTorisel · 4.5 · Temsirolimus has been associated with phospholipidosis in rats. Phospholipidosis has not been observed in mice
Eintrag öffnenTorisel · 4.5 · The combination of temsirolimus and sunitinib resulted in dose-limiting toxicity. Dose-limiting toxicities (Gr
Eintrag öffnenTorisel · 4.5 · The effect of a 175 or 75 mg temsirolimus dose on CYP3A4/5 substrates has not been studied. However, in vitro
Eintrag öffnenTorisel · 4.8 · Cataracts have been observed in some patients who received the combination of temsirolimus and IFN-α.
Eintrag öffnenTorisel · 4.8 · Serious adverse reactions observed in clinical trials of temsirolimus for MCL, but not in clinical trials of t
Eintrag öffnenTorisel · 4.8 · Serious adverse reactions observed in clinical trials of temsirolimus for advanced RCC, but not in clinical tr
Eintrag öffnenTorisel · 4.8 · The most serious reactions observed with temsirolimus in clinical trials are hypersensitivity/infusion reactio
Eintrag öffnenTorisel · 4.8 · The occurrence of undesirable effects following the dose of 175 mg temsirolimus/week for MCL, e.g. Grade 3 or
Eintrag öffnenTwynsta · 4.5 · Mechanistic Target of Rapamycin (mTOR) Inhibitors mTOR inhibitors such as sirolimus, temsirolimus, and everoli
Eintrag öffnenTwynsta · 4.5 · Mechanistic Target of Rapamycin (mTOR) Inhibitors mTOR inhibitors such as sirolimus, temsirolimus, and everoli
Eintrag öffnenTwynsta · 4.5 · Mechanistic Target of Rapamycin (mTOR) Inhibitors mTOR inhibitors such as sirolimus, temsirolimus, and everoli
Eintrag öffnenTwynsta · 4.5 · Mechanistic Target of Rapamycin (mTOR) Inhibitors mTOR inhibitors such as sirolimus, temsirolimus, and everoli
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