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Tigecyclin
Eintrag öffnenTygacil · 4.3 · Patients hypersensitive to tetracycline class antibiotics may be hypersensitive to tigecycline.
Eintrag öffnenTygacil · 4.5 · 5 (aPTT), the relevant coagulation tests should be closely monitored when tigecycline is co-administered with
Eintrag öffnenTygacil · 4.5 · Based on an in vitro study tigecycline is a P-gp substrate. Co-administration of P-gp inhibitors (e.g., ketoco
Eintrag öffnenTygacil · 4.5 · Concomitant administration of tigecycline and warfarin (25 mg single-dose) to healthy subjects resulted in a d
Eintrag öffnenTygacil · 4.5 · Concomitant use of tigecycline and calcineurin inhibitors such as tacrolimus or cyclosporine may lead to an in
Eintrag öffnenTygacil · 4.5 · Tigecycline in recommended dosage did not affect the rate or extent of absorption, or clearance of digoxin (0.
Eintrag öffnenTygacil · 4.5 · Tigecycline is not extensively metabolised. Therefore, clearance of tigecycline is not expected to be affected
Eintrag öffnenTygacil · 4.8 · 8 Tigecycline may be associated with permanent tooth discolouration if used during tooth development (see sect
Eintrag öffnenTygacil · 4.8 · AST and ALT abnormalities in tigecycline-treated patients were reported more frequently in the post therapy pe
Eintrag öffnenTygacil · 4.8 · Adverse reactions reported with tigecycline, including clinical trials and post-marketing experience, are tabu
Eintrag öffnenTygacil · 4.8 · In an open-label, single ascending dose PK study, the safety of tigecycline was investigated in 25 children ag
Eintrag öffnenTygacil · 4.8 · The safety of tigecycline was also investigated in an open-label, ascending multi-dose PK study in 58 children
Eintrag öffnenTygacil · 4.8 · The total number of cSSTI and cIAI patients treated with tigecycline in Phase 3 and 4 clinical studies was 2,3
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